Yechun Xu
Overview
Explore the profile of Yechun Xu including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
141
Citations
5077
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Xiong M, Nie T, Li Z, Hu M, Su H, Hu H, et al.
J Chem Inf Model
. 2024 Nov;
64(24):9501-9516.
PMID: 39605253
3-Chymotrypsin-like protease (3CL) is a prominent target against pathogenic coronaviruses. Expert knowledge of the cysteine-targeted covalent reaction mechanism is crucial to predict the inhibitory potency of approved inhibitors against 3CLs...
2.
Wang X, Xiong L, Zhu Y, Liu S, Zhao W, Wu X, et al.
J Am Chem Soc
. 2024 Nov;
146(49):33983-33996.
PMID: 39574309
The COVID-19 pandemic, exacerbated by persistent viral mutations, underscored the urgent need for diverse inhibitors targeting multiple viral proteins. In this study, we utilized covalent DNA-encoded libraries to discover innovative...
3.
Zhou Y, Tan J, Huang L, Ye Y, Xu Y
Int J Mol Sci
. 2024 Oct;
25(20).
PMID: 39456923
T. L. Wu, an endemic species in China, is listed as a key protected wild plant in Guangdong Province. However, the lack of reports on the chloroplast genome and simple...
4.
Zhou Y, Xu Y, Tan J, Huang L, Zhu G, Ye Y
Plant Physiol Biochem
. 2024 Sep;
216:109156.
PMID: 39341180
Anthocyanins are one of the key metabolites influencing the coloration of ornamental bracts in plants. Curcuma alismatifolia is an emerging ornamental plant, known for the rich diversity in the coloration...
5.
Jiang Z, Feng B, Chen L, Nie T, Chen S, Wang L, et al.
J Med Chem
. 2024 Jul;
67(15):12760-12783.
PMID: 39072488
SARS-CoV-2 has still been threatening global public health with its emerging variants. Our previous work reported lead compound that displayed good 3CL inhibitory activity. Here, an in-depth structural optimization for...
6.
Lu W, Cui J, Wang W, Hu Q, Xue Y, Liu X, et al.
Nat Commun
. 2024 Jun;
15(1):4703.
PMID: 38830868
Nuclear factor erythroid 2-related factor 2 (NRF2) hyperactivation has been established as an oncogenic driver in a variety of human cancers, including non-small cell lung cancer (NSCLC). However, despite massive...
7.
Wang X, Zhu Y, Zhao Q, Lu W, Xu Y, Hu H, et al.
ACS Med Chem Lett
. 2024 Apr;
15(4):555-564.
PMID: 38628804
DNA-encoded library (DEL) technology is gaining attention for its rapid construction and deconvolution capabilities. Our study explored a novel strategy using rational DELs tailored for the SARS-CoV-2 papain-like protease, which...
8.
Gu C, Liu J, Qian F, Yu W, Huang D, Shen J, et al.
J Med Chem
. 2024 Mar;
67(6):4855-4869.
PMID: 38489246
Atopic dermatitis is a chronic relapsing skin disease characterized by recurrent, pruritic, localized eczema, while PDE4 inhibitors have been reported to be effective as antiatopic dermatitis agents. 3',4--dimethylcedrusin (DCN) is...
9.
Qin Y, Li D, Qi C, Xiang H, Meng H, Liu J, et al.
Acta Pharm Sin B
. 2024 Jan;
14(1):319-334.
PMID: 38261830
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) functions as a key regulator in inflammation and cell death and is involved in mediating a variety of inflammatory or degenerative diseases. A number of...
10.
Cao B, Wang Y, Lu H, Huang C, Yang Y, Shang L, et al.
N Engl J Med
. 2024 Jan;
390(3):230-241.
PMID: 38231624
Background: Simnotrelvir is an oral 3-chymotrypsin-like protease inhibitor that has been found to have in vitro activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and potential efficacy in a...