Wuyan Chen
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Explore the profile of Wuyan Chen including associated specialties, affiliations and a list of published articles.
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40
Citations
733
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Recent Articles
1.
Bekheirnia N, Glinton K, Rossetti L, Manor J, Chen W, Lamb D, et al.
Kidney360
. 2022 Apr;
2(1):90-104.
PMID: 35368817
Background: As genetic testing increasingly integrates into the practice of nephrology, our understanding of the basis of many kidney disorders has exponentially increased. Given this, we recently initiated a Renal...
2.
Li B, Wang L, Ge H, Zhang X, Ren P, Guo Y, et al.
Front Chem
. 2021 Aug;
9:659764.
PMID: 34368076
COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still an emergent pandemic for humans. The virus infection is achieved by penetrating its spike protein to host cells...
3.
Finn E, Kripps K, Chambers C, Rapp M, Meeks N, Xu F, et al.
J Investig Med High Impact Case Rep
. 2021 May;
9:23247096211014685.
PMID: 33966472
Lipoid congenital adrenal hyperplasia (LCAH) is typically inherited as an autosomal recessive condition. There are 3 reports of individuals with a dominantly acting heterozygous variant leading to a clinically significant...
4.
Lao Q, Mallappa A, Rueda Faucz F, Joyal E, Veeraraghavan P, Chen W, et al.
Mol Genet Genomic Med
. 2020 Dec;
9(2):e1556.
PMID: 33332743
Background: Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is an autosomal recessive disease of steroidogenesis that affects 1 in 15,000. Approximately, 10% of the CAH population also suffer from...
5.
Liu Z, Hu Q, Wang W, Lu S, Wu D, Ze S, et al.
Biochem Pharmacol
. 2020 May;
177:114000.
PMID: 32353424
Multiple sclerosis (MS) is the most popular chronic and debilitating inflammatory disease of the central nervous system (CNS) that remains incurable. Dihydroorotate dehydrogenase (DHODH) is critical to the activity of...
6.
Shen R, Zhou J, Li G, Chen W, Zhong W, Chen Z
Neurosci Lett
. 2019 Dec;
717:134654.
PMID: 31785308
Background: SS31 has been shown to have neuroprotective effects in a number of neurological degenerative diseases. However, the mechanisms and its role of neuroprotection after subarachnoid hemorrhage (SAH) remain unexplored....
7.
Zhang X, Dong G, Li H, Chen W, Li J, Feng C, et al.
J Med Chem
. 2019 May;
62(11):5579-5593.
PMID: 31099559
Psoriasis is a common, chronic inflammatory disease characterized by abnormal skin plaques, and the effectiveness of phosphodiesterase 4 (PDE4) inhibitor to lessen the symptoms of psoriasis has been proved. Aiming...
8.
Wu D, Wang W, Chen W, Lian F, Lang L, Huang Y, et al.
Haematologica
. 2018 Jun;
103(9):1472-1483.
PMID: 29880605
Acute myeloid leukemia is a disorder characterized by abnormal differentiation of myeloid cells and a clonal proliferation derived from primitive hematopoietic stem cells. Interventions that overcome myeloid differentiation have been...
9.
Hannah-Shmouni F, Morissette R, Sinaii N, Elman M, Prezant T, Chen W, et al.
Genet Med
. 2017 May;
19(11):1276-1279.
PMID: 28541281
PurposeNonclassic 21-hydroxylase deficiency, a mild form of congenital adrenal hyperplasia (CAH), is estimated to be the most common autosomal recessive condition, with an especially high prevalence in Ashkenazi Jews (3.7%...
10.
Hannah-Shmouni F, Chen W, Merke D
Endocrinol Metab Clin North Am
. 2017 May;
46(2):435-458.
PMID: 28476231
Congenital adrenal hyperplasia (CAH) refers to a group of autosomal recessive disorders due to single-gene defects in the various enzymes required for cortisol biosynthesis. CAH represents a continuous phenotypic spectrum...