Yaxue Zhao
Overview
Explore the profile of Yaxue Zhao including associated specialties, affiliations and a list of published articles.
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35
Citations
526
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Recent Articles
1.
Zhou Q, Zhang Z, Gao L, Li G, Zhang Y, Yang W, et al.
J Chem Theory Comput
. 2025 Mar;
PMID: 40029701
Aptamers, functional nucleic acids recognized for their high target-binding affinity and specificity, have been extensively employed in biosensors, diagnostics, and therapeutics. Conventional screening methods apply evolutionary pressure to optimize affinity,...
2.
Rong F, Bao W, Li G, Ge Y, Zhu W, Hao B, et al.
Angew Chem Int Ed Engl
. 2025 Jan;
:e202423527.
PMID: 39817307
Hydrogen sulfide (HS) plays crucial inflammatory modulating roles, representing a promising candidate for anti-inflammatory therapies. However, current HS delivery approaches lack sufficient specificity against inflammatory response. Herein, regarding the overexpressed...
3.
Qin Y, Li G, Wang L, Yin G, Zhang X, Wang H, et al.
Bioorg Chem
. 2024 Mar;
146:107291.
PMID: 38521011
Hyaluronidase is a promising target in drug discovery, given its overexpression in a range of physiological and pathological processes, including tumor migration, skin aging, sagging, and wrinkling, as well as...
4.
Zhang Y, Zhou T, Qi Y, Li Y, Zhang Y, Zhao Y, et al.
J Control Release
. 2023 Dec;
365:521-529.
PMID: 38040342
Changing positions of amino acid residues in the peptide sequence alters the peptide' s assembly behaviors, affording various nanostructures. However, it remains elusive that how subtle changes in the peptide...
5.
Zhang Y, Chen S, Choi T, Qi Y, Wang Q, Li G, et al.
J Comput Aided Mol Des
. 2023 Jun;
37(7):301-312.
PMID: 37286854
Cell division control protein 42 homolog (Cdc42), which controls a variety of cellular functions including rearrangements of the cell cytoskeleton, cell differentiation and proliferation, is a potential cancer therapeutic target....
6.
Zhang Y, Li G, Zhao Y
Bioorg Med Chem
. 2023 May;
90:117337.
PMID: 37253305
Rho guanosine triphosphatases (Rho GTPases), as members of the Ras superfamily, are GDP/GTP binding proteins that behave as molecular switches for the transduction of signals from external stimuli. Rho GTPases...
7.
Chen S, Zhang Z, Zhang Y, Choi T, Zhao Y
Int J Mol Sci
. 2022 Dec;
23(24).
PMID: 36555100
RhoA, a member of Rho GTPases, regulates myriad cellular processes. Abnormal expression of RhoA has been implicated in various diseases, including cancers, developmental disorders and bacterial infections. RhoA mutations G14V...
8.
Ullah S, Junaid M, Liu Y, Chen S, Zhao Y, Wadood A
Mol Divers
. 2022 Aug;
27(3):1323-1332.
PMID: 35932436
Post-translational modifications of proteins such as protein ubiquitination are crucial for regulating conformation, stability and localization of the modified protein. Ubiquitin-specific protease 2 (USP2), a multifunctional cysteine protease is reported...
9.
Zhu Y, Wu L, Zhao Y, Wang Z, Lu J, Yu Y, et al.
Phytomedicine
. 2022 Apr;
100:154085.
PMID: 35405616
Background: Bombesin Receptor Subtype-3 (BRS-3, Bombesin-like receptor, BB) is an orphan G-protein coupled receptor (GPCR). Recent studies have shown that BRS-3 played a vital role in glucose regulation, insulin secretion,...
10.
Chen S, Shu L, Zhao R, Zhao Y
Proteins
. 2022 Feb;
90(7):1376-1389.
PMID: 35152498
Cell division control protein 42 homolog (Cdc42), which contributes to multiple cellular processes including cell proliferation and migration, is a potential target for cancer therapy, especially in the intervention of...