Yasuyo Harada
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Explore the profile of Yasuyo Harada including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
436
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Recent Articles
1.
Harada Y, Sasaki T, Obata-Ninomiya K, Matsuyama T, Ueha S, Shichino S, et al.
Res Sq
. 2025 Feb;
PMID: 39989951
Cutaneous allergen sensitization (CAS) underlies atopic dermatitis (AD) and leads to various allergic symptoms, including food allergy and anaphylaxis. IL-13 expression by T follicular helper T (T) has been reported...
2.
Kubo M, Harada Y, Sasaki T
Int Immunol
. 2024 Aug;
36(11):559-566.
PMID: 39162776
Allergy is a complex array of diseases influenced by innate and adaptive immunity, genetic polymorphisms, and environmental triggers. Atopic dermatitis is a chronic inflammatory skin disease characterized by barrier defects...
3.
Kagohashi K, Sasaki Y, Ozawa K, Tsuchiya T, Kawahara S, Saitoh K, et al.
J Immunol
. 2024 Feb;
212(6):951-961.
PMID: 38315039
Signal-transducing adaptor protein (STAP)-1 is an adaptor protein that is widely expressed in T cells. In this article, we show that STAP-1 upregulates TCR-mediated T cell activation and T cell-mediated...
4.
Okuyama K, Nomura A, Nishino K, Tanaka H, Harly C, Chihara R, et al.
J Immunol
. 2023 Apr;
210(11):1728-1739.
PMID: 37074186
Posttranslational modification, such as phosphorylation, is an important biological event that modulates and diversifies protein function. Bcl11b protein is a zinc-finger transcription factor that plays a crucial role in early...
5.
Miyauchi K, Adachi Y, Tonouchi K, Yajima T, Harada Y, Fukuyama H, et al.
Nat Commun
. 2021 Jun;
12(1):3789.
PMID: 34145279
Influenza viruses are a major public health problem. Vaccines are the best available countermeasure to induce effective immunity against infection with seasonal influenza viruses; however, the breadth of antibody responses...
6.
Miyauchi K, Sugimoto-Ishige A, Harada Y, Adachi Y, Usami Y, Kaji T, et al.
Nat Immunol
. 2016 Nov;
17(12):1447-1458.
PMID: 27798619
Virus infection induces the development of T follicular helper (T) and T helper 1 (T1) cells. Although T cells are important in anti-viral humoral immunity, the contribution of T1 cells...
7.
Ozaki N, Suzuki S, Ishida M, Harada Y, Tanaka K, Sato Y, et al.
Int Immunol
. 2012 Aug;
24(9):539-50.
PMID: 22914861
Spleen tyrosine kinase (Syk) is associated with Fcγ receptors (FcγRs) and transmits activation signals through FcγRs in myeloid cells. Thus, application of drugs to inhibit Syk activity can affect the...
8.
Harada Y, Tanaka S, Motomura Y, Harada Y, Ohno S, Ohno S, et al.
Immunity
. 2012 Feb;
36(2):188-200.
PMID: 22365664
A main role for interleukin-4 (IL-4) is in humoral immunity, and follicular helper CD4(+) T (Tfh) cells may be an intrinsic IL-4 source. Here we demonstrate that conserved noncoding sequence...
9.
Sawaguchi M, Tanaka S, Nakatani Y, Harada Y, Mukai K, Matsunaga Y, et al.
J Immunol
. 2012 Jan;
188(4):1809-18.
PMID: 22250079
We established a diphtheria toxin (DT)-based conditional deletion system using Il4 enhancer elements previously shown to be specific for IL-4 production in mast cells (MCs) or basophils (Mas-TRECK and Bas-TRECK...
10.
Harada Y, Harada Y, Elly C, Ying G, Paik J, DePinho R, et al.
J Exp Med
. 2010 May;
207(7):1381-91.
PMID: 20439537
The transcription factor Foxp3 is essential for optimal regulatory T (T reg) cell development and function. Here, we show that CD4(+) T cells from Cbl-b RING finger mutant knockin or...