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Takanori Sasaki

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Articles 108
Citations 734
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Recent Articles
1.
Harada Y, Sasaki T, Obata-Ninomiya K, Matsuyama T, Ueha S, Shichino S, et al.
Res Sq . 2025 Feb; PMID: 39989951
Cutaneous allergen sensitization (CAS) underlies atopic dermatitis (AD) and leads to various allergic symptoms, including food allergy and anaphylaxis. IL-13 expression by T follicular helper T (T) has been reported...
2.
Sasaki T, Kimura S, Noda A, Murakami Y, Miyoshi S, Akehi M, et al.
Nucl Med Biol . 2025 Feb; 144-145:109001. PMID: 39985867
Background: Preclinical pharmacokinetic studies of therapeutic antibodies in non-human primates are desired because of the difficulty in extrapolating ADME data from animal models to humans. We evaluated the pharmacokinetics of...
3.
Kanno J, Shoji T, Ishii H, Ibuki H, Yoshikawa Y, Sasaki T, et al.
Transl Vis Sci Technol . 2025 Feb; 14(2):22. PMID: 39982396
Purpose: This study investigates factors influencing visual acuity logarithmic minimum angle of resolution (logMAR) in idiopathic macular holes (IMH), with a focus on the foveal avascular zone (FAZ). Methods: En...
4.
Sasaki T, Sowerby J, Xiao Y, Wang R, Marks K, Horisberger A, et al.
bioRxiv . 2025 Feb; PMID: 39974998
Pathologic T cell-B cell interactions drive disease in systemic lupus erythematosus (SLE). The T cells that activate B cell responses include T peripheral helper (Tph) and T follicular helper (Tfh)...
5.
Miyamoto S, Dehari H, Tokura T, Sasaki T, Igarashi T, Shimura S, et al.
J Oral Implantol . 2025 Feb; PMID: 39906931
Extensive resections of the maxillary bone often result in significant defects that affect oral functions such as speech and chewing. Although dentomaxillary prostheses are common, they frequently lead to instability...
6.
Klimek K, Chen X, Sasaki T, Groener D, Werner R, Higuchi T
Mol Metab . 2024 Oct; 90:102055. PMID: 39454827
Background: Sodium-glucose cotransporters (SGLTs) play a crucial role in glucose regulation and are essential therapeutic targets for diabetes management. Recent advancements have leveraged SGLT-targeted PET imaging to examine these transporters'...
7.
Wang Z, Kushibiki H, Tarusawa T, Osonoi S, Ogasawara S, Miura C, et al.
J Neurochem . 2024 Oct; 169(2):e16235. PMID: 39453752
Diabetic polyneuropathy (DPN) is a multifactorial disease associated not only with hyperglycaemia but also with circulatory disturbances such as hypertension. A close interaction between the immune system and hypertension is...
8.
Schorr K, Chen X, Sasaki T, Arias-Loza A, Lang J, Higuchi T, et al.
ACS Pharmacol Transl Sci . 2024 Sep; 7(9):2604-2611. PMID: 39296255
Thin-layer chromatography (TLC) is commonly employed to screen technetium-99m labeled polymer nanoparticle batches for unreduced pertechnetate and radio-colloidal impurities. Although this method is widely accepted, our findings applying radiolabeled PLGA/PLA-PEG...
9.
Yakushi A, Sugimoto M, Sasaki T
Comput Biol Chem . 2024 Sep; 113:108204. PMID: 39270542
The tertiary lymphoid structure (TLS) plays a central role in cancer immune response, and its gene expression pattern, called the TLS signature, has shown prognostic value in breast cancer. The...
10.
Kubo M, Harada Y, Sasaki T
Int Immunol . 2024 Aug; 36(11):559-566. PMID: 39162776
Allergy is a complex array of diseases influenced by innate and adaptive immunity, genetic polymorphisms, and environmental triggers. Atopic dermatitis is a chronic inflammatory skin disease characterized by barrier defects...