Yasushi Fujitani
Overview
Explore the profile of Yasushi Fujitani including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
16
Citations
499
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0
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Recent Articles
1.
Watanabe K, Peyrin-Biroulet L, Danese S, Fujitani Y, Faes M, Oortwijn A, et al.
J Crohns Colitis
. 2023 Nov;
18(6):801-811.
PMID: 38019901
Background And Aims: SELECTION is the first study to assess the impact of concomitant thiopurine and other immunomodulator [IM] use on the efficacy and safety of a Janus kinase inhibitor,...
2.
Mizushima T, Ota M, Fujitani Y, Kanauchi Y, Iwakiri R
Crohns Colitis 360
. 2023 Feb;
3(3):otab055.
PMID: 36776659
Background: Perianal fistula (PAF) is a disabling complication of Crohn's disease (CD) which greatly impacts the quality of life. To address a scarcity of data in Asian populations, we determined...
3.
Fukase Y, Sato A, Tomata Y, Ochida A, Kono M, Yonemori K, et al.
Bioorg Med Chem
. 2018 Jan;
26(3):721-736.
PMID: 29342416
Novel small molecules were synthesized and evaluated as retinoic acid receptor-related orphan receptor-gamma t (RORγt) inverse agonists for the treatment of inflammatory and autoimmune diseases. A hit compound, 1, was...
4.
Shirai J, Tomata Y, Kono M, Ochida A, Fukase Y, Sato A, et al.
Bioorg Med Chem
. 2017 Dec;
26(2):483-500.
PMID: 29262987
A series of novel phenylglycinamides as retinoic acid receptor-related orphan receptor-gamma t (RORγt) inverse agonists were discovered through optimization of a high-throughput screen hit 1. (R)-N-(2-((3,5-Difluoro-4-(trimethylsilyl)phenyl) amino)-1-(4-methoxyphenyl)-2-oxoethyl)-3-hydroxy-N-methylisoxazole-5-carboxamide (22) was identified...
5.
Kono M, Oda T, Tawada M, Imada T, Banno Y, Taya N, et al.
Bioorg Med Chem
. 2017 Dec;
26(2):470-482.
PMID: 29258712
A series of tetrahydroisoquinoline derivatives were designed, synthesized, and evaluated for their potential as novel orally efficacious retinoic acid receptor-related orphan receptor-gamma t (RORγt) inverse agonists for the treatment of...
6.
Fujisawa D, Kashiwakura J, Kita H, Kikukawa Y, Fujitani Y, Sasaki-Sakamoto T, et al.
J Allergy Clin Immunol
. 2014 Jun;
134(3):622-633.e9.
PMID: 24954276
Background: Wheal reactions to intradermally injected neuropeptides, such as substance P (SP) and vasoactive intestinal peptide, are significantly larger and longer lasting in patients with chronic urticaria (CU) than in...
7.
8.
Itomi Y, Sagara M, Fujitani Y, Kawamura T, Takizawa M
Nihon Yakurigaku Zasshi
. 2013 Aug;
142(2):68-72.
PMID: 23934525
No abstract available.
9.
Terao Y, Suzuki H, Yoshikawa M, Yashiro H, Takekawa S, Fujitani Y, et al.
Bioorg Med Chem Lett
. 2012 Nov;
22(24):7326-9.
PMID: 23147077
Imidazo[1,2-a]pyridine derivatives were designed, synthesized, and evaluated as inhibitors of the apoptosis signal-regulating kinase 1 (ASK1). These were based on a benzothiazole derivative that was discovered from high-throughput screening of...
10.
Fujitani Y, Aritake K, Kanaoka Y, Goto T, Takahashi N, Fujimori K, et al.
FEBS J
. 2010 Feb;
277(6):1410-9.
PMID: 20136655
Lipocalin-type prostaglandin (PG) D synthase is expressed in adipose tissues and involved in the regulation of glucose tolerance and atherosclerosis in type 2 diabetes. However, the physiological roles of PGD(2)...