Yaniv Lubling
Overview
Explore the profile of Yaniv Lubling including associated specialties, affiliations and a list of published articles.
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21
Citations
4168
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Recent Articles
1.
Rappoport N, Chomsky E, Nagano T, Seibert C, Lubling Y, Baran Y, et al.
Nat Commun
. 2023 Jun;
14(1):3844.
PMID: 37386027
Embryonic development involves massive proliferation and differentiation of cell lineages. This must be supported by chromosome replication and epigenetic reprogramming, but how proliferation and cell fate acquisition are balanced in...
2.
van der Leun A, Hoekstra M, Reinalda L, Scheele C, Toebes M, van de Graaff M, et al.
Nat Chem Biol
. 2021 Sep;
17(11):1139-1147.
PMID: 34504322
The functional activity and differentiation potential of cells are determined by their interactions with surrounding cells. Approaches that allow unbiased characterization of cell states while at the same time providing...
3.
Ros S, Wright A, DSantos P, Hu D, Hesketh R, Lubling Y, et al.
Cancer Cell
. 2020 Sep;
38(4):516-533.e9.
PMID: 32976773
PIK3CA, encoding the PI3Kα isoform, is the most frequently mutated oncogene in estrogen receptor (ER)-positive breast cancer. Isoform-selective PI3K inhibitors are used clinically but intrinsic and acquired resistance limits their...
4.
Li H, van der Leun A, Yofe I, Lubling Y, Gelbard-Solodkin D, van Akkooi A, et al.
Cell
. 2020 May;
181(3):747.
PMID: 32359441
No abstract available.
5.
Baran Y, Bercovich A, Sebe-Pedros A, Lubling Y, Giladi A, Chomsky E, et al.
Genome Biol
. 2019 Oct;
20(1):206.
PMID: 31604482
scRNA-seq profiles each represent a highly partial sample of mRNA molecules from a unique cell that can never be resampled, and robust analysis must separate the sampling effect from biological...
6.
Li H, van der Leun A, Yofe I, Lubling Y, Gelbard-Solodkin D, van Akkooi A, et al.
Cell
. 2019 Jan;
176(4):775-789.e18.
PMID: 30595452
Tumor immune cell compositions play a major role in response to immunotherapy, but the heterogeneity and dynamics of immune infiltrates in human cancer lesions remain poorly characterized. Here, we identify...
7.
Giladi A, Paul F, Herzog Y, Lubling Y, Weiner A, Yofe I, et al.
Nat Cell Biol
. 2018 Jun;
20(7):836-846.
PMID: 29915358
The dynamics of haematopoietic stem cell differentiation and the hierarchy of oligopotent stem cells in the bone marrow remain controversial. Here we dissect haematopoietic progenitor populations at single cell resolution,...
8.
Bonev B, Mendelson Cohen N, Szabo Q, Fritsch L, Papadopoulos G, Lubling Y, et al.
Cell
. 2017 Oct;
171(3):557-572.e24.
PMID: 29053968
Chromosome conformation capture technologies have revealed important insights into genome folding. Yet, how spatial genome architecture is related to gene expression and cell fate remains unclear. We comprehensively mapped 3D...
9.
Nagano T, Lubling Y, Varnai C, Dudley C, Leung W, Baran Y, et al.
Nature
. 2017 Jul;
547(7661):61-67.
PMID: 28682332
Chromosomes in proliferating metazoan cells undergo marked structural metamorphoses every cell cycle, alternating between highly condensed mitotic structures that facilitate chromosome segregation, and decondensed interphase structures that accommodate transcription, gene...
10.
Olivares-Chauvet P, Mukamel Z, Lifshitz A, Schwartzman O, Elkayam N, Lubling Y, et al.
Nature
. 2016 Dec;
540(7632):296-300.
PMID: 27919068
Chromosomes are folded into highly compacted structures to accommodate physical constraints within nuclei and to regulate access to genomic information. Recently, global mapping of pairwise contacts showed that loops anchoring...