Y van Kooyk
Overview
Explore the profile of Y van Kooyk including associated specialties, affiliations and a list of published articles.
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71
Citations
3557
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Recent Articles
31.
Bleijs D, Binnerts M, van Vliet S, Figdor C, van Kooyk Y
J Cell Sci
. 2000 Jan;
113 ( Pt 3):391-400.
PMID: 10639327
Although ICAM-3 is implicated in both adhesion and signal transduction events of leukocytes, its low affinity for LFA-1 compared to other ligands of LFA-1 has puzzled many investigators. Here we...
32.
Tanaka Y, Minami Y, Mine S, Hirano H, Hu C, Fujimoto H, et al.
J Immunol
. 1999 Nov;
163(11):6209-16.
PMID: 10570313
The adhesive function of integrins is regulated through cytoplasmic signaling. The present study was performed to investigate the relevance of cytoplasmic signaling and cytoskeletal assembly to integrin-mediated adhesion induced by...
33.
van Kooyk Y, van Vliet S, Figdor C
J Biol Chem
. 1999 Sep;
274(38):26869-77.
PMID: 10480895
To elucidate the role of the cytoskeleton regulating avidity or affinity changes in the leukocyte adhesion receptor lymphocyte function-associated antigen-1 (LFA-1) (alpha(L)beta(2)), we generated mutant cytoplasmic LFA-1 receptors and expressed...
34.
Bleijs D, Figdor C, van Kooyk Y
Eur J Immunol
. 1999 Jul;
29(7):2248-58.
PMID: 10427988
The LFA-1 adhesion molecule is involved in cell adhesion events of leukocytes through binding to ICAM-1, ICAM-2 and ICAM-3. Whether binding to either of these ligands similarly affects co-stimulation of...
35.
Peters I, van Kooyk Y, van Vliet S, de Grooth B, Figdor C, Greve J
Cytometry
. 1999 Jul;
36(3):189-94.
PMID: 10404967
A three-dimensional single-particle tracking system was combined with an optical trap to investigate the behavior of transmembrane adhesion proteins. We exploited this setup to investigate which part of the cell...
36.
Geijtenbeek T, van Kooyk Y, van Vliet S, Renes M, Raymakers R, Figdor C
Blood
. 1999 Jul;
94(2):754-64.
PMID: 10397743
Aberrant proliferation, differentiation, and/or migration of progenitors observed in various hematological malignancies may be caused by defects in expression and/or function of integrins. In this study, we have developed a...
37.
Fibbe W, Pruijt J, Velders G, Opdenakker G, van Kooyk Y, Figdor C, et al.
Ann N Y Acad Sci
. 1999 Jun;
872:71-82.
PMID: 10372112
The CXC chemokine interleukin-8 (IL-8) has profound hematopoietic activities following systemic administration. It induces the rapid mobilization of cells with lymphomyeloid repopulating ability in mice and of hematopoietic progenitor cells...
38.
Binnerts M, van Kooyk Y
Immunol Today
. 1999 May;
20(5):240-5.
PMID: 10322304
The integrin leukocyte function-associated antigen 1 (LFA-1) is pivotal for cell adhesion and signalling within the immune system. Here, Minke Binnerts and Yvette van Kooyk discuss evidence from mutational and...
39.
Pruijt J, van Kooyk Y, Figdor C, Willemze R, Fibbe W
Blood
. 1998 Dec;
93(1):107-12.
PMID: 9864152
Recently, we have demonstrated that antibodies that block the function of the beta2-integrin leukocyte function-associated antigen-1 (LFA-1) completely abrogate the rapid mobilization of hematopoietic progenitor cells (HPC) with colony-forming and...
40.
van Kooyk Y, Lub M, Figdor C
Cell Adhes Commun
. 1998 Nov;
6(2-3):247-54.
PMID: 9823475
Integrins not only mediate cell adhesion but also contribute to a variety of other cellular processes including proliferation, cytokine production, cytotoxicity and apoptosis. They act as bi-directional signal transducers, mediating...