Y van Kooyk
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Explore the profile of Y van Kooyk including associated specialties, affiliations and a list of published articles.
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71
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3557
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Recent Articles
21.
van Kooyk Y, Figdor C
Curr Opin Cell Biol
. 2000 Sep;
12(5):542-7.
PMID: 10978887
The activity of integrins on leukocytes is tightly controlled, and their adhesion capacity shifts rapidly when cells emigrate from the blood to the tissues. The leukocyte-specific beta2 integrin LFA-1 (alphaLbeta2)...
22.
Wanten G, Geijtenbeek T, Raymakers R, van Kooyk Y, Roos D, Jansen J, et al.
JPEN J Parenter Enteral Nutr
. 2000 Jul;
24(4):228-33.
PMID: 10885717
Background: To test the hypothesis that lipid emulsions with different triglyceride structures have distinct immunomodulatory properties, we analyzed human neutrophil adhesion and degranulation after lipid incubation. Methods: Neutrophils, isolated from...
23.
Sigal A, Bleijs D, Grabovsky V, van Vliet S, Dwir O, Figdor C, et al.
J Immunol
. 2000 Jun;
165(1):442-52.
PMID: 10861083
The LFA-1 integrin is crucial for the firm adhesion of circulating leukocytes to ICAM-1-expressing endothelial cells. In the present study, we demonstrate that LFA-1 can arrest unstimulated PBL subsets and...
24.
Nelissen J, Peters I, de Grooth B, van Kooyk Y, Figdor C
Mol Biol Cell
. 2000 Jun;
11(6):2057-68.
PMID: 10848629
Restricted expression of activated leukocyte cell adhesion molecule (ALCAM) by hematopoietic cells suggests an important role in the immune system and hematopoiesis. To get insight into the mechanisms that control...
25.
Geiger C, Nagel W, Boehm T, van Kooyk Y, Figdor C, Kremmer E, et al.
EMBO J
. 2000 Jun;
19(11):2525-36.
PMID: 10835351
Intracellular signaling pathways, which regulate the interactions of integrins with their ligands, affect a wide variety of biological functions. Here we provide evidence of how cytohesin-1, an integrin-binding protein and...
26.
Nelissen J, Torensma R, Pluyter M, Adema G, Raymakers R, van Kooyk Y, et al.
Exp Hematol
. 2000 Apr;
28(4):422-32.
PMID: 10781900
Objective: Osteoblasts play an important role in regulating hematopoiesis in the bone marrow. Here we show that U2-OS, a widely used osteoblastic cell line derived from an osteosarcoma, has the...
27.
Reedquist K, Ross E, Koop E, Wolthuis R, Zwartkruis F, van Kooyk Y, et al.
J Cell Biol
. 2000 Mar;
148(6):1151-8.
PMID: 10725328
Integrin-mediated leukocyte adhesion is a critical aspect of leukocyte function that is tightly regulated by diverse stimuli, including chemokines, antigen receptors, and adhesion receptors. How cellular signals from CD31 and...
28.
Geijtenbeek T, Kwon D, Torensma R, van Vliet S, van Duijnhoven G, Middel J, et al.
Cell
. 2000 Mar;
100(5):587-97.
PMID: 10721995
Dendritic cells (DC) capture microorganisms that enter peripheral mucosal tissues and then migrate to secondary lymphoid organs, where they present these in antigenic form to resting T cells and thus...
29.
Geijtenbeek T, Torensma R, van Vliet S, van Duijnhoven G, Adema G, van Kooyk Y, et al.
Cell
. 2000 Mar;
100(5):575-85.
PMID: 10721994
Contact between dendritic cells (DC) and resting T cells is essential to initiate a primary immune response. Here, we demonstrate that ICAM-3 expressed by resting T cells is important in...
30.
Fibbe W, Pruijt J, van Kooyk Y, Figdor C, Opdenakker G, Willemze R
Semin Hematol
. 2000 Mar;
37(1 Suppl 2):19-24.
PMID: 10718155
The chemokine interleukin-8 (IL-8) is a potent chemoattractant and activator of neutrophils. Upon systemic injection, IL-8 induces an immediate neutropenia followed by a rebound granulocytosis. In this report, we discuss...