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Xuekang Zhang

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Articles 11
Citations 44
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Recent Articles
1.
Liu Z, Liu Q, Zhang X, Li G
Chem Biol Drug Des . 2025 Jan; 105(1):e70022. PMID: 39757387
Cerebral ischemia/reperfusion injury (IRI) is pathologically associated with ferroptosis. Dexmedetomidine (Dex) exerts neuroprotective activity after cerebral IRI. Our work focused on probing the pharmacologic effect of Dex on ferroptosis during...
2.
Wu Q, Chen Q, Liang S, Nie J, Wang Y, Fan C, et al.
Mol Med . 2024 Nov; 30(1):203. PMID: 39508252
Intestinal ischemia/reperfusion injury (I/R) is a common yet challenging-to-treat condition, presenting a significant clinical challenge. This study aims to investigate the protective mechanisms of Dexmedetomidine (Dex) against I/R injury, with...
3.
Wei X, Chen Z, He M, Xu L, Li Y, Yang J, et al.
RSC Adv . 2024 Aug; 14(33):24055-24065. PMID: 39086525
Mg-Fe layered hydroxide (LDH) was synthesized by the double titration method and added to trimesoyl chloride (TMC) to prepare an Mg-Fe LDH-modified polyamide nanofiltration (NF) membrane by interfacial polymerization (IP)....
4.
Huang Y, Chen T, Jiang M, Xiong C, Mei C, Nie J, et al.
Cell Death Dis . 2024 Jan; 15(1):29. PMID: 38212319
Intestinal ischemia-reperfusion (II/R) injury is an urgent clinical disease with high incidence and mortality, and impaired intestinal barrier function caused by excessive apoptosis of intestinal cells is an important cause...
5.
Chen L, Fan C, Zhang X, Chen S, Ye L, Zheng X
J Toxicol Sci . 2023 Nov; 48(11):585-595. PMID: 37914286
Objective: Lidocaine has been reported to induce neurotoxicity, which is further enhanced by high glucose levels. This study is aimed to explore the underlying mechanisms of lidocaine neurotoxicity in spinal...
6.
Hu Q, Liu X, Liu Z, Liu Z, Zhang H, Zhang Q, et al.
J Cell Mol Med . 2022 Apr; 26(9):2594-2606. PMID: 35366055
This study was performed to uncover the effects of dexmedetomidine on oxidative stress injury induced by mitochondrial localization of telomerase reverse transcriptase (TERT) in enteric glial cells (EGCs) following intestinal...
7.
Huang Y, Xiao Y, Zhang X, Huang X, Li Y
J Immunol Res . 2021 Oct; 2021:1007126. PMID: 34712740
Acute lung injury (ALI) is an inflammatory disorder of the lung that causes high mortality and lacks any pharmacological intervention. Ubiquitination plays a critical role in the pathogenesis of ALI...
8.
Xu L, Li T, Chen Q, Liu Z, Chen Y, Hu K, et al.
J Cell Mol Med . 2021 Jun; PMID: 34114328
Intestinal ischaemia-reperfusion (I/R) injury can result in acute lung injury due to ischaemia and hypoxia. Dexmedetomidine (Dex), a highly selective alpha2-noradrenergic receptor (α2AR) agonist used in anaesthesia, is reported to...
9.
Zhang X, Zhou J, Hu Q, Liu Z, Chen Q, Wang W, et al.
J Nanosci Nanotechnol . 2019 Oct; 20(5):3295-3302. PMID: 31635678
Dexmedetomidine (Dex) works as a crucial agent for the treatment of intestinal ischemia/reperfusion (I/R), but its mechanism remains unclear. Recent articles demonstrated the pivotal role of Janus kinase/signal transducer and...
10.
Liu X, Liu J, Zhang X, Tong Y, Gan X
J Cell Mol Med . 2018 Nov; 23(1):205-215. PMID: 30407707
Although the non-small cell lung cancer (NSCLC) is one of the most malignant tumours worldwide, the mechanisms controlling NSCLC tumourigenesis remain unclear. Here, we find that the expression of miR-520b...