Xin-Yun Lu
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Explore the profile of Xin-Yun Lu including associated specialties, affiliations and a list of published articles.
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51
Citations
1724
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Recent Articles
1.
Gharpure M, Vyavahare S, Asante D, Chen J, Zhong R, Cooley M, et al.
Geroscience
. 2025 Jan;
PMID: 39875754
Alzheimer's disease (AD), a progressive neurodegenerative disorder, is frequently associated with musculoskeletal complications, including sarcopenia and osteoporosis, which substantially impair patient quality of life. Despite these clinical observations, the molecular...
2.
Veerapaneni P, Goo B, Ahmadieh S, Shi H, Kim D, Ogbi M, et al.
Biomolecules
. 2024 Apr;
14(4).
PMID: 38672510
Histone deacetylase (HDAC) 9 is a negative regulator of adipogenic differentiation, which is required for maintenance of healthy adipose tissues. We reported that expression is upregulated in adipose tissues during...
3.
Alterations in Alzheimer's disease microglia transcriptome might be involved in bone pathophysiology
Gharpure M, Vyavahare S, Ahluwalia P, Gupta S, Lee T, Lohakare J, et al.
Neurobiol Dis
. 2024 Jan;
191:106404.
PMID: 38184014
Aging is a major risk factor for multiple chronic disorders in the elderly population, including Alzheimer's disease (AD) and Osteoporosis. AD is a progressive neurodegenerative disease characterized by memory loss....
4.
Ahmadieh S, Goo B, Zarzour A, Kim D, Shi H, Veerapaneni P, et al.
Obesity (Silver Spring)
. 2023 Oct;
32(1):107-119.
PMID: 37869960
Objective: Impaired adipogenic differentiation exacerbates metabolic disease in obesity. This study reported that high-fat diet (HFD)-fed mice housed at thermoneutrality exhibited impaired adipogenic differentiation, attributed to increased expression of histone...
5.
Shi X, Ding K, Rosario R, Ajith A, Su Y, Shaw S, et al.
J Gerontol A Biol Sci Med Sci
. 2023 Oct;
79(2).
PMID: 37855709
This study investigates the effects of peroxisome proliferator-activated receptor gamma (PPARγ) inhibition on bone and immune cell profiles in aged female mice, as well as in vitro stromal stem cell...
6.
Xiang G, Liu X, Wang J, Lu S, Yu M, Zhang Y, et al.
Transl Psychiatry
. 2023 Jun;
13(1):206.
PMID: 37322045
The dentate gyrus (DG) of the hippocampus encodes contextual information associated with fear, and cell activity in the DG is required for acquisition and extinction of contextual fear. However, the...
7.
Kumro J, Tripathi A, Lei Y, Sword J, Callahan P, Terry A, et al.
Cereb Cortex
. 2023 Mar;
33(12):7627-7641.
PMID: 36939283
The etiology of Alzheimer's dementia has been hypothesized in terms of basal forebrain cholinergic decline, and in terms of reflecting beta-amyloid neuropathology. To study these different biological elements, we activated...
8.
Fang X, Chen Y, Wang J, Zhang Z, Bai Y, Denney K, et al.
Mol Psychiatry
. 2022 Dec;
28(3):1365-1382.
PMID: 36473997
Chronic stress exposure induces maladaptive behavioral responses and increases susceptibility to neuropsychiatric conditions. However, specific neuronal populations and circuits that are highly sensitive to stress and trigger maladaptive behavioral responses...
9.
Miller B, McEvoy J, McCall W, Lu X
Schizophr Res
. 2022 Nov;
250:134-136.
PMID: 36410289
No abstract available.
10.
Saggu S, Chen Y, Cottingham C, Rehman H, Wang H, Zhang S, et al.
Mol Psychiatry
. 2022 Nov;
28(2):588-600.
PMID: 36357671
Posttraumatic stress disorder (PTSD) after the pandemic has emerged as a major neuropsychiatric component of post-acute COVID-19 syndrome, yet the current pharmacotherapy for PTSD is limited. The use of adrenergic...