Stanley J Watson
Overview
Explore the profile of Stanley J Watson including associated specialties, affiliations and a list of published articles.
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145
Citations
7937
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Recent Articles
1.
Anderson A, Moyers B, Loupe J, Rodriguez-Nunez I, Felker S, Lawlor J, et al.
Genome Res
. 2024 Aug;
34(8):1224-1234.
PMID: 39152038
Transcription factors (TFs) regulate gene expression by facilitating or disrupting the formation of transcription initiation machinery at particular genomic loci. Because TF occupancy is driven in part by recognition of...
2.
Loupe J, Anderson A, Rizzardi L, Rodriguez-Nunez I, Moyers B, Trausch-Lowther K, et al.
Nat Neurosci
. 2024 Jun;
27(7):1387-1399.
PMID: 38831039
Transcription factors (TFs) orchestrate gene expression programs crucial for brain function, but we lack detailed information about TF binding in human brain tissue. We generated a multiomic resource (ChIP-seq, ATAC-seq,...
3.
Wei Q, Kumar V, Moore S, Li F, Murphy G, Watson S, et al.
Neurobiol Stress
. 2023 Nov;
27:100581.
PMID: 37928820
Emotions are characterized not only by their valence but also by whether they are stable or labile. Yet, we do not understand the molecular or circuit mechanisms that control the...
4.
Moyers B, Loupe J, Felker S, Lawlor J, Anderson A, Rodriguez-Nunez I, et al.
bioRxiv
. 2023 Oct;
PMID: 37873117
Transcription Factors (TFs) influence gene expression by facilitating or disrupting the formation of transcription initiation machinery at particular genomic loci. Because genomic localization of TFs is in part driven by...
5.
Anderson A, Rogers B, Loupe J, Rodriguez-Nunez I, Roberts S, White L, et al.
Cell Genom
. 2023 Mar;
3(3):100263.
PMID: 36950385
Cell type-specific transcriptional differences between brain tissues from donors with Alzheimer's disease (AD) and unaffected controls have been well documented, but few studies have rigorously interrogated the regulatory mechanisms responsible...
6.
Hjelm B, Ramiro C, Rollins B, Omidsalar A, Gerke D, Das S, et al.
Complex Psychiatry
. 2023 Feb;
8(3-4):90-98.
PMID: 36778651
Introduction: Large somatic deletions of mitochondrial DNA (mtDNA) accumulate with aging in metabolically active tissues such as the brain. We have cataloged the breakpoints and frequencies of large mtDNA deletions...
7.
Bossert J, Mejias-Aponte C, Saunders T, Altidor L, Emery M, Fredriksson I, et al.
J Neurosci
. 2023 Jan;
43(10):1692-1713.
PMID: 36717230
The brain µ-opioid receptor (MOR) is critical for the analgesic, rewarding, and addictive effects of opioid drugs. However, in rat models of opioid-related behaviors, the circuit mechanisms of MOR-expressing cells...
8.
Parsegian A, Garcia-Fuster M, Hebda-Bauer E, Watson S, Flagel S, Akil H
Front Psychiatry
. 2022 Oct;
13:1024617.
PMID: 36311521
Adolescent drug use reliably predicts increased addiction liability in adulthood, but not all individuals are equally impacted. To explore the biological bases of this differential reactivity to early life drug...
9.
Das S, Hjelm B, Rollins B, Sequeira A, Morgan L, Omidsalar A, et al.
Transl Psychiatry
. 2022 Aug;
12(1):353.
PMID: 36042222
Mitochondrial dysfunction is a neurobiological phenomenon implicated in the pathophysiology of schizophrenia and bipolar disorder that can synergistically affect synaptic neurotransmission. We hypothesized that schizophrenia and bipolar disorder share molecular...
10.
Mamdani F, Weber M, Bunney B, Burke K, Cartagena P, Walsh D, et al.
Transl Psychiatry
. 2022 Apr;
12(1):159.
PMID: 35422091
Suicides have increased to over 48,000 deaths yearly in the United States. Major depressive disorder (MDD) is the most common diagnosis among suicides, and identifying those at the highest risk...