Jacob C Garza
Overview
Explore the profile of Jacob C Garza including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
14
Citations
622
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Piguel N, Yoon S, Gao R, Horan K, Garza J, Petryshen T, et al.
Neuropsychopharmacology
. 2022 Nov;
48(7):1000-1010.
PMID: 36376465
Bipolar disorder (BD) is a highly heritable mood disorder with intermittent episodes of mania and depression. Lithium is the first-in-line medication to treat BD, but it is only effective in...
2.
Bowles K, Silva M, Whitney K, Bertucci T, Berlind J, Lai J, et al.
Cell
. 2021 Jul;
184(17):4547-4563.e17.
PMID: 34314701
Frontotemporal dementia (FTD) because of MAPT mutation causes pathological accumulation of tau and glutamatergic cortical neuronal death by unknown mechanisms. We used human induced pluripotent stem cell (iPSC)-derived cerebral organoids...
3.
4.
Li C, Meng F, Garza J, Liu J, Lei Y, Kirov S, et al.
Mol Psychiatry
. 2020 Jan;
26(8):4205-4220.
PMID: 31980728
The adipocyte-derived hormone adiponectin has a broad spectrum of functions beyond metabolic control. We previously reported that adiponectin acts in the brain to regulate depression-related behaviors. However, its underlying neural...
5.
Garza J, Qi X, Gjeluci K, Leussis M, Basu H, Reis S, et al.
Transl Psychiatry
. 2018 Jul;
8(1):135.
PMID: 30046097
The ankyrin 3 gene (ANK3) is a well-established risk gene for psychiatric illness, but the mechanisms underlying its pathophysiology remain elusive. We examined the molecular effects of disrupting brain-specific Ank3...
6.
Petryshen T, Lewis M, Dennehy K, Garza J, Fava M
Neurosci Lett
. 2016 Apr;
620:70-3.
PMID: 27033002
Current medications for depression typically require weeks of treatment before significant clinical improvement is observed, and are only effective in a relatively small subset of patients. Recent human clinical studies...
7.
Guo M, Huang T, Garza J, Chua S, Lu X
Int J Neuropsychopharmacol
. 2012 Aug;
16(4):857-67.
PMID: 22932068
Previous studies have demonstrated that leptin and its receptors (LepRb) in the central nervous system play an important role in regulating depression- and anxiety-related behaviours. However, the physiological functions of...
8.
Guo M, Lu Y, Garza J, Li Y, Chua S, Zhang W, et al.
Transl Psychiatry
. 2012 Mar;
2:e83.
PMID: 22408745
The glutamatergic system has been implicated in the pathophysiology of depression and the mechanism of action of antidepressants. Leptin, an adipocyte-derived hormone, has antidepressant-like properties. However, the functional role of...
9.
Liu J, Garza J, Li W, Lu X
Int J Neuropsychopharmacol
. 2011 Dec;
16(1):105-20.
PMID: 22176700
The central melanocortin system has been implicated in emotional stress-induced anxiety, anorexia and activation of the hypothalamo-pituitary-adrenal (HPA) axis. However, the underlying neural substrates have not been identified. The medial...
10.
Liu J, Garza J, Bronner J, Kim C, Zhang W, Lu X
Psychopharmacology (Berl)
. 2009 Oct;
207(4):535-45.
PMID: 19823809
Rationale: Our previous studies in rats have shown that the adipocyte-derived hormone leptin induces antidepressant-like effects with a behavioral profile similar to selective serotonin reuptake inhibitor (SSRI) antidepressants. Acute SSRI...