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Xin-Ying Yang

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Articles 39
Citations 348
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Recent Articles
1.
Yang X, Wang S, Xue W, Zhang Y, Li L, Luo Z, et al.
Antioxid Redox Signal . 2024 Aug; 42(4-6):228-248. PMID: 39135387
Nattokinase (NK), a potent serine endopeptidase, has exhibited a variety of pharmacological effects, including thrombolysis, anti-inflammation, and antioxidative stress. Building on previous research highlighting NK's promise in nerve regeneration, our...
2.
Wang P, Zhu W, Wang Y, Song S, Xi Y, Yang X, et al.
Eur J Med Chem . 2023 Aug; 259:115709. PMID: 37567056
Poly(ADP-ribose) polymerase 1 (PARP1) inhibitors can selectively kill homologous recombination (HR) deficient cancer cells and elicit anticancer effect through a mechanism of synthetic lethality. In this study, we designed, synthesized...
3.
Wang L, Wang P, Chen X, Yang H, Song S, Song Z, et al.
EMBO Mol Med . 2023 Jan; 15(3):e16235. PMID: 36652375
Poly-ADP-ribose polymerase (PARP) inhibitors (PARPi) have shown great promise for treating BRCA-deficient tumors. However, over 40% of BRCA-deficient patients fail to respond to PARPi. Here, we report that thioparib, a...
4.
Yang X, Han T, Lv J
Front Pediatr . 2022 Oct; 10:1001775. PMID: 36299686
We initially described two children who developed Guillain-Barré syndrome (GBS) complicated by rhabdomyolysis (RML), and reviewed five adult patients from the literature. Through analysis of the clinical features, laboratory examination,...
5.
Song B, Wang C, Yao X, Yang L, Zhang W, Wang Z, et al.
Biochem J . 2020 Dec; 477(24):4811. PMID: 33367592
No abstract available.
6.
Li J, Fang F, Ren X, Zhang W, Yang X, Ren C, et al.
Zhongguo Dang Dai Er Ke Za Zhi . 2020 Sep; 22(9):964-969. PMID: 32933627
Objective: To evaluate the efficacy and safety of tacrolimus in the treatment of children with myasthenia gravis (MG). Methods: A total of 28 children with MG were treated with tacrolimus....
7.
Feng W, Yang X, Li J, Gong S, Wu Y, Zhang W, et al.
Front Genet . 2020 Mar; 11:126. PMID: 32194620
Familial hemophagocytic lymphohistiocytosis Type 2 (FHL2) associated central nervous system (CNS) involvement is less understood in children, especially when considering neurologic manifestations as part of the initial presentation. We conducted...
8.
Jiao M, You H, Yang X, Yuan H, Li Y, Liu W, et al.
Sci Rep . 2018 Jan; 8(1):724. PMID: 29335596
Circulating miRNAs are proposed as a biomarker of heart disease. This study evaluated whether circulating miRNAs could be used as a biomarker for childhood dilated cardiomyopathy (CDCM). A total of...
9.
Yang Z, Liao X, Chen Y, Shen Y, Yang X, Su Y, et al.
Acta Pharmacol Sin . 2017 Apr; 38(7):1038-1047. PMID: 28414200
Over half of patients with BRCA1-deficient cancers do not respond to treatment with poly(ADP-ribose) polymerase (PARP) inhibitors. In this study, we report that a combination of 53BP1 and BRCA1 may...
10.
Xu Y, Wang X, Chen Y, Chen S, Yang X, Sun Y, et al.
Theranostics . 2017 Apr; 7(4):974-986. PMID: 28382169
PI3Kα-selective inhibitor BYL719 is currently in phase II/III clinical trial for the treatment of breast cancer, but highly variable response has been observed among patients. We sought to discover predictive...