Xiao-Yi Zeng
Overview
Explore the profile of Xiao-Yi Zeng including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
429
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Recent Articles
11.
Zeng X, Wang H, Bai F, Zhou X, Li S, Ren L, et al.
Br J Pharmacol
. 2015 Jun;
172(17):4303-18.
PMID: 26040411
Background And Purpose: Matrine is a small molecule drug used in humans for the treatment of chronic viral infections and tumours in the liver with little adverse effects. The present...
12.
Chan S, Zeng X, Sun R, Jo E, Zhou X, Wang H, et al.
Biochim Biophys Acta
. 2015 Apr;
1852(7):1511-9.
PMID: 25906681
Hepatic steatosis is often associated with insulin resistance as a hallmark of the metabolic syndrome in the liver. The present study investigated the effects of PPARα activation induced by fenofibrate...
13.
Chen Y, Zeng X, He Y, Liu H, Wang B, Zhou H, et al.
ACS Chem Biol
. 2015 Apr;
10(6):1570-1.
PMID: 25905901
No abstract available.
14.
Cai G, Dinan T, Barwood J, De Luca S, Soch A, Ziko I, et al.
Front Neurosci
. 2015 Jan;
8:446.
PMID: 25628527
Neonatal obesity predisposes individuals to obesity throughout life. In rats, neonatal overfeeding also leads to early accelerated weight gain that persists into adulthood. The phenotype is associated with dysfunction in...
15.
IRE1 impairs insulin signaling transduction of fructose-fed mice via JNK independent of excess lipid
Sun R, Wang H, Zeng X, Chan S, Li S, Jo E, et al.
Biochim Biophys Acta
. 2014 Dec;
1852(1):156-65.
PMID: 25458704
The unfolded protein response (UPR) pathways have been implicated in the development of hepatic insulin resistance during high fructose (HFru) feeding. The present study investigated their roles in initiating impaired...
16.
Wang H, Sun R, Zeng X, Zhou X, Li S, Jo E, et al.
Endocrinology
. 2014 Oct;
156(1):169-81.
PMID: 25343276
High-carbohydrate (mainly fructose) consumption is a major dietary factor for hepatic insulin resistance, involving endoplasmic reticulum (ER) stress and lipid accumulation. Because autophagy has been implicated in ER stress, the...
17.
Zhou X, Zeng X, Wang H, Li S, Jo E, Xue C, et al.
PLoS One
. 2014 Sep;
9(9):e107231.
PMID: 25222566
Our recent study (referred as Study 1) showed that the triterpenoid oleanolic acid (OA) was able to produce a sustained correction of hyperglycemia beyond treatment period in type 2 diabetes...
18.
Chen Y, Zeng X, He Y, Liu H, Wang B, Zhou H, et al.
ACS Chem Biol
. 2013 Aug;
8(10):2301-11.
PMID: 23962138
Obesity is characterized by expansion of adipose tissue, which results from an increase in adipocyte number (adipogenesis) and adipocyte size (lipogenesis). A reversal of these processes has been suggested to...
19.
Iseli T, Turner N, Zeng X, Cooney G, Kraegen E, Yao S, et al.
PLoS One
. 2013 May;
8(4):e62309.
PMID: 23638033
We recently showed that bitter melon-derived triterpenoids (BMTs) activate AMPK and increase GLUT4 translocation to the plasma membrane in vitro, and improve glucose disposal in insulin resistant models in vivo....
20.
Chan S, Sun R, Zeng X, Choong Z, Wang H, Watt M, et al.
Diabetes
. 2013 Jan;
62(6):2095-105.
PMID: 23349482
Endoplasmic reticulum (ER) stress is suggested to cause hepatic insulin resistance by increasing de novo lipogenesis (DNL) and directly interfering with insulin signaling through the activation of the c-Jun N-terminal...