Xiao-Long Shi
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Explore the profile of Xiao-Long Shi including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
23
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Recent Articles
1.
Xun Q, Zhang J, Feng L, Ma Y, Li Y, Shi X
J Enzyme Inhib Med Chem
. 2025 Feb;
40(1):2466846.
PMID: 39976249
Herein, a novel pyrrolo[2,3-]pyridine-based glycogen synthase kinase 3β (GSK-3β) inhibitor, , was rationally designed and synthesised to target Alzheimer's disease (AD). inhibited GSK-3β, with an IC of 0.35 ± 0.06 ...
2.
Xun Q, Zhang J, Li Y, Li Y, Ma Y, Chen Z, et al.
Eur J Med Chem
. 2025 Jan;
285:117236.
PMID: 39798400
The development of potent glycogen synthase kinase-3β (GSK-3β) inhibitor has been increasingly recognized as the candidate treatment against the multifactorial pathogenic mechanism of Alzheimer's disease (AD). This study prepared various...
3.
Shi X, Chen S, Guo G, Yang Y, Tong K, Cao W, et al.
Taiwan J Obstet Gynecol
. 2024 May;
63(3):369-374.
PMID: 38802200
Objective: To explore a precise association between tumor location and lymph node (LN) biopsy algorithm in uterine confined endometrial cancer (EC). Materials And Methods: Patients with EC treated in the...
4.
Dai Z, Zhu P, Liu H, Li X, Zhu Y, Liu Y, et al.
Phytomedicine
. 2022 Jul;
104:154335.
PMID: 35858515
Background: In recent years, the T-cell therapy and immune checkpoint inhibitors toward CTLA-4 and PD-1/PD-L1 axis antibody therapy have acquired encouraging success. However, most of patients were still not benefited...
5.
Yan N, Shi X, Tang L, Wang D, Li X, Liu C, et al.
J Enzyme Inhib Med Chem
. 2022 Jun;
37(1):1724-1736.
PMID: 35698879
Glycogen synthase kinase 3β (GSK-3β) catalyses the hyperphosphorylation of tau protein in the Alzheimer's disease (AD) pathology. A series of novel thieno[3,2-]pyrazol-3-amine derivatives were designed and synthesised and evaluated as...
6.
Shi X, Yan N, Cui Y, Liu Z
Cells
. 2020 Mar;
9(3).
PMID: 32155989
Due to the complicated pathogenesis of Alzheimer's disease (AD), the development of multitargeted agents to simultaneously interfere with multiple pathological processes of AD is a potential choice. Glycogen synthase kinase-3β...
7.
Shi X, Wu J, Liu P, Liu Z
Eur J Med Chem
. 2019 Feb;
167:211-225.
PMID: 30772605
To target the multi-facets of Alzheimer's disease (AD), a series of novel GSK-3β inhibitors containing the 2,3-diaminopyridine moiety were designed and synthesized. The amide derivatives 5a-f showed moderate potency against...
8.
Zheng X, Jiang Y, Shi X
Zhongguo Zhong Xi Yi Jie He Za Zhi
. 2009 Aug;
29(5):410-3.
PMID: 19673330
Objective: To investigate the typical features of contrast-enhanced ultrasound imaging in malignant lymphoma after treatment with integrated Chinese and Western medicine. Methods: Ten patients with malignant lymphoma after different treatment...
9.
Zheng X, Zhang Y, Zhao C, Shi X, Li C, Jiang J, et al.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
. 2009 Jun;
44(4):277-81.
PMID: 19558831
Objective: To explore the value of contrast-enhanced ultrasound (CEUS) in the diagnosis of thyroid occupied lesions with injection of sulphur hexafluoride microbubbles. Methods: Fifty nine cases of conventional ultrasonic diagnosis...