Xian-Zhang Bu
Overview
Explore the profile of Xian-Zhang Bu including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
322
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Recent Articles
1.
Lou L, Li W, Zhou B, Chen L, Weng H, Zou Y, et al.
Phytother Res
. 2018 Oct;
33(1):214-223.
PMID: 30375049
Cardiac fibrosis contributes to both systolic and diastolic dysfunction in many cardiac pathophysiologic conditions. Antifibrotic therapies are likely to be a crucial strategy in curbing many fibrosis-related cardiac diseases. In...
2.
Sun Z, Chen Y, Guo Y, Qiu J, Zhu C, Jin J, et al.
Bioorg Med Chem Lett
. 2015 Feb;
25(6):1240-3.
PMID: 25682561
Fifteen taxanes (1-15) including a new taxane glucoside, 7β,9α,10β-triacetoxy-13α-hydroxy-5α-O-(β-d-glucopyranosyl)taxa-4(20),11-diene (1), were isolated from the barks of Taxus wallichiana var. mairei. Compounds 1-15 representing three sub-types of 6/8/6-taxane were evaluated in...
3.
Liu H, Liu Y, Zhang F, Wang H, Zhang G, Zhou B, et al.
Mol Biosyst
. 2014 Mar;
10(6):1320-31.
PMID: 24651282
Curcumin (diferuloylmethane) is a polyphenol natural product of the plant Curcuma longa, and has a diversity of antitumor activities. However, the clinical application of curcumin remains limited due to its...
4.
Shang N, Shao Y, Cai Y, Guan M, Huang M, Cui W, et al.
Biochem Pharmacol
. 2014 Feb;
89(1):86-98.
PMID: 24565909
Phosphodiesterase-5 (PDE5) inhibitors have been approved for the treatment of erectile dysfunction and pulmonary hypertension, but enthusiasm on discovery of PDE5 inhibitors continues for their potential new applications. Reported here...
5.
Wang X, Wang H, Zhang F, Guo Q, Wang H, Wang K, et al.
Eur J Immunol
. 2013 Oct;
44(1):173-83.
PMID: 24114072
Nodal, a member of the TGF-β superfamily, is an embryonic morphogen that is upregulated in different types of tumors. Nodal increases the tumorigenesis by inducing angiogenesis and promoting metastasis. Importantly,...
6.
Xu J, Jia Y, Chen S, Ye J, Bu X, Hu Y, et al.
Int Immunopharmacol
. 2013 Mar;
15(4):743-51.
PMID: 23499680
Flavonoids are a class of compounds that exist in nature with the structure of 2-phenyl-chromone. In Chinese traditional medicine, herbal drugs containing flavonoids are widely used for the treatment of...
7.
Wang H, Wang H, Zhou B, Li C, Zhang F, Wang X, et al.
PLoS One
. 2013 Feb;
8(2):e56664.
PMID: 23431386
Chronic inflammation-promoted metastasis has been considered as a major challenge in cancer therapy. Pro-inflammatory cytokine TNFα can induce cancer invasion and metastasis associated with epithelial-mesenchymal transition (EMT). However, the underlying...
8.
Liu H, Zhou B, Qiu X, Wang H, Zhang F, Fang R, et al.
Free Radic Biol Med
. 2012 Oct;
53(12):2204-17.
PMID: 23085518
Curcumin (diferuloylmethane) is a natural polyphenol product of the plant Curcuma longa and has a diversity of antitumor activities. T63, a new 4-arylidene curcumin analogue, was reported to inhibit proliferation...
9.
Xiao G, Liang B, Chen S, Ou T, Bu X, Yan M
Arch Pharm (Weinheim)
. 2012 Jul;
345(10):767-70.
PMID: 22836584
A series of 3-nitrochromenes were designed and synthesized. These compounds showed good inhibitory activity against thioredoxin reductase (TrxR) and the proliferation of A549 cancer cells. The structure-activity relationship analysis indicates...
10.
Yi Y, Zhang G, Zeng J, Huang S, Li L, Fang R, et al.
Cancer Biol Ther
. 2011 Mar;
11(10):866-73.
PMID: 21372637
Indolamine2, 3-dioxygenase (IDO) is expressed in tumor antigen presenting cells (APCs) and plays an important role in tumor immune tolerance. Inhibiting its activity may break tumor immune tolerance and thus...