Woojin An
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Explore the profile of Woojin An including associated specialties, affiliations and a list of published articles.
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61
Citations
2362
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Recent Articles
11.
Ghate N, Kim S, Spiller E, Kim S, Shin Y, Rhie S, et al.
Mol Oncol
. 2021 Jul;
15(10):2801-2817.
PMID: 34312968
Histone modification is aberrantly regulated in cancer and generates an unbalanced state of gene transcription. VprBP, a recently identified kinase, phosphorylates histone H2A on threonine 120 (T120) and is involved...
12.
Rice J, Weekley B, Kanholm T, Chen Z, Lee S, Fernandez D, et al.
Epigenetics Chromatin
. 2021 May;
14(1):23.
PMID: 34001241
Background: Selective proteolysis of the histone H3 N-terminal tail (H3NT) is frequently observed during eukaryotic development, generating a cleaved histone H3 (H3cl) product within a small, but significant, portion of...
13.
Situ A, Kim J, An W, Kim C, Ulmer T
J Mol Biol
. 2021 Feb;
433(7):166832.
PMID: 33539882
The inhibition of physiological activation pathways of the platelet adhesion receptor integrin αIIbβ3 may fail to prevent fatal thrombosis, suggesting that the receptor is at risk of activation by yet...
14.
An W, Heo J, Jang D, Euh K, Jung I, Kim S, et al.
J Nanosci Nanotechnol
. 2020 Jul;
20(11):6890-6896.
PMID: 32604532
The microstructural evolution of Al-Zn-Mg-Cu alloys has been investigated for the homogenization time effect on the texture, grain orientation and dislocation density. The Al-Zn-Mg-Cu alloys were casted and homogenized for...
15.
Zhang L, He A, Chen B, Bi J, Chen J, Guo D, et al.
Genome Res
. 2020 Jan;
30(2):155-163.
PMID: 31953347
Temozolomide (TMZ) is a frequently used chemotherapy for glioma; however, chemoresistance is a major problem limiting its effectiveness. Thus, knowledge of mechanisms underlying this outcome could improve patient prognosis. Here,...
16.
Shin Y, Lee S, Namkoong E, An W, Lee J, Brown P, et al.
Int J Mol Sci
. 2019 Dec;
20(24).
PMID: 31847128
Anoctamin1 (ANO1), a calcium activated chloride channel, is known to play a critical role in salivary secretion. In the salivary gland, ANO1 is expressed exclusively in the acinar cells, with...
17.
Ghate N, Kim J, Shin Y, Situ A, Ulmer T, An W
Mol Oncol
. 2019 Jul;
13(9):1976-1992.
PMID: 31293051
p53 is a sequence-specific transcription factor, and proper regulation of p53 transcriptional activity is critical for orchestrating different tumor-suppressive mechanisms. p32 is a multifunctional protein which interacts with a large...
18.
Shin Y, Ghate N, Moon B, Park K, Lu W, An W
Epigenetics Chromatin
. 2019 Apr;
12(1):25.
PMID: 30992059
Background: MMP-9-dependent proteolysis of histone H3 N-terminal tail (H3NT) is an important mechanism for activation of gene expression during osteoclast differentiation. Like other enzymes targeting their substrates within chromatin structure,...
19.
Kim J, Shin Y, Lee S, Kim M, Punj V, Lu J, et al.
Cell Rep
. 2018 Jul;
24(1):224-237.
PMID: 29972783
Breast cancer cells relocate to bone and activate osteoclast-induced bone resorption. Soluble factors secreted by breast cancer cells trigger a cascade of events that stimulate osteoclast differentiation in the bone...
20.
Kim J, Shin Y, Lee S, Kim M, Punj V, Shin H, et al.
Oncogene
. 2018 Jun;
37(43):5749-5765.
PMID: 29925860
Osteoclasts are multinuclear bone-resorbing cells that differentiate from hematopoietic precursor cells. Prostate cancer cells frequently spread to bone and secrete soluble signaling factors to accelerate osteoclast differentiation and bone resorption....