Kyu Heo
Overview
Explore the profile of Kyu Heo including associated specialties, affiliations and a list of published articles.
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Articles
52
Citations
1138
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Recent Articles
1.
Eum D, Lee C, Tran C, Lee J, Park S, Jeong M, et al.
Toxicol Res
. 2024 Jun;
40(3):409-419.
PMID: 38911538
Echinochrome A (Ech A), a marine biosubstance isolated from sea urchins, is a strong antioxidant, and its clinical form, histochrome, is being used to treat several diseases, such as ophthalmic,...
2.
Eum D, Jeong M, Park S, Kim J, Jin Y, Jo J, et al.
PLoS One
. 2024 Apr;
19(4):e0296989.
PMID: 38625901
Natural anmindenol A isolated from the marine-derived bacteria Streptomyces sp. caused potent inhibition of inducible nitric oxide synthase without any significant cytotoxicity. This compound consists of a structurally unique 3,10-dialkylbenzofulvene...
3.
Jin Y, Eum D, Lee C, Park S, Shim J, Choi Y, et al.
Mol Carcinog
. 2024 Jan;
63(4):714-727.
PMID: 38251858
The histone variant, macroH2A (mH2A) influences gene expression through epigenetic regulation. Tumor suppressive function of mH2A isoforms has been reported in various cancer types, but few studies have investigated the...
4.
Park S, Eum D, Jin Y, Lee C, Shim J, Choi S, et al.
Oncol Lett
. 2023 Nov;
26(6):521.
PMID: 37927420
The complement system is a powerful innate immune system deployed in the immediate response to pathogens and cancer cells. Complement factor H (CFH), one of the regulators involved in the...
5.
Jin Y, Park S, Park S, Lee C, Eum D, Shim J, et al.
Int J Mol Sci
. 2022 Jan;
23(2).
PMID: 35054776
Epigenetic abnormalities affect tumor progression, as well as gene expression and function. Among the diverse epigenetic modulators, the histone methyltransferase G9a has been focused on due to its role in...
6.
Jung S, Lee C, Lee K, Heo K, Choi S
Nucleic Acids Res
. 2021 Jun;
49(15):e85.
PMID: 34086942
CRISPR-Cas9 is a powerful tool for genome engineering, but its efficiency largely depends on guide RNA (gRNA). There are multiple methods available to evaluate the efficiency of gRNAs, including the...
7.
Jin Y, Choi Y, Heo K, Park S
Int J Mol Sci
. 2021 Jan;
22(1).
PMID: 33406787
Breast cancer is the most common type of cancer. In the developmental stages of breast cancer, estrogens are strongly involved. As estrogen synthesis is regulated by the enzyme aromatase, targeting...
8.
Song J, Eum D, Park S, Jin Y, Shim J, Park S, et al.
PLoS One
. 2020 Oct;
15(10):e0240533.
PMID: 33091036
Ginsenoside Rg3 (Rg3) has been studied in several cancer models and is suggested to act through various pharmacological effects. We investigated the anticancer properties of Rg3 through myeloid-derived suppressor cell...
9.
Kim H, Moon S, Kim S, Heo K, Kim J
Cell Death Dis
. 2018 Aug;
9(8):831.
PMID: 30082743
Metastasis-associated in colon cancer 1 (MACC1) has been reported to be overexpressed in multiple cancers and promote proliferation, metastasis, cancer stem cell-like properties, and drug resistance of cancer cells. Despite...
10.
Jeon H, Kim Y, Kim J, Heo K, Pyo J, Yamaguchi M, et al.
Mech Ageing Dev
. 2018 Apr;
173:50-60.
PMID: 29625135
Chromatin change is one of the crucial causes of aging. Specifically, maintenance of heterochromatin stability is critical for cellular integrity, and its loss induces genomic instability and cellular aging. However,...