Wolfgang Huber
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Explore the profile of Wolfgang Huber including associated specialties, affiliations and a list of published articles.
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345
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96620
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Recent Articles
1.
Chong S, Lu J, Valentin R, Lehmberg T, Eu J, Wang J, et al.
Mol Cancer
. 2025 Mar;
24(1):62.
PMID: 40025512
Background: Established genetic biomarkers in chronic lymphocytic leukemia (CLL) have been useful in predicting response to chemoimmunotherapy but are less predictive of response to targeted therapies. With several such targeted...
2.
Kolbe C, Kauer J, Brinkmann B, Dreger P, Huber W, Muller-Tidow C, et al.
J Immunother Cancer
. 2025 Jan;
13(1).
PMID: 39884778
Bispecific antibodies (BsAb) have emerged as a leading treatment modality in patients suffering from B-cell non-Hodgkin's lymphoma (B-NHL). However, treatment failure is common and may potentially be attributed to pre-existing...
3.
Smirnov P, Przybilla M, Simovic-Lorenz M, Parra R, Susak H, Ratnaparkhe M, et al.
Nat Commun
. 2025 Jan;
16(1):1085.
PMID: 39870666
No abstract available.
4.
Pohly M, Putzker K, Scheinost S, Ben Taarit L, Walther T, Kummer S, et al.
Blood
. 2025 Jan;
PMID: 39869826
T-cell prolymphocytic leukemia (T-PLL) is an aggressive lymphoid malignancy with limited treatment options. To discover new treatment targets for T-PLL, we performed high-throughput drug sensitivity screening on 30 primary patient...
5.
Ahlmann-Eltze C, Huber W
Nat Genet
. 2025 Jan;
57(3):659-667.
PMID: 39753773
Identifying gene expression differences in heterogeneous tissues across conditions is a fundamental biological task, enabled by multi-condition single-cell RNA sequencing (RNA-seq). Current data analysis approaches divide the constituent cells into...
6.
Geographical factors and air raid alarms influence leptospirosis epidemiology in Ukraine (2018-2023)
Petakh P, Huber W, Kamyshnyi O
One Health
. 2024 Dec;
19:100944.
PMID: 39679281
Leptospirosis, a widespread zoonotic disease caused by spp., affects approximately 1 million people annually and causes about 58,000 deaths worldwide. This study examines the epidemiology of leptospirosis in Ukraine from...
7.
Smirnov P, Przybilla M, Simovic-Lorenz M, Parra R, Susak H, Ratnaparkhe M, et al.
Nat Commun
. 2024 Nov;
15(1):10183.
PMID: 39580568
Chromothripsis is a frequent form of genome instability, whereby a presumably single catastrophic event generates extensive genomic rearrangements of one or multiple chromosome(s). However, little is known about the heterogeneity...
8.
Capraz T, Huber W
Bioinformatics
. 2024 Sep;
40(9).
PMID: 39254597
Motivation: A fundamental step in many analyses of high-dimensional data is dimension reduction. Two basic approaches are introduction of new synthetic coordinates and selection of extant features. Advantages of the...
9.
Gegner H, Naake T, Aljakouch K, Dugourd A, Kliewer G, Muller T, et al.
Clin Proteomics
. 2024 Jul;
21(1):49.
PMID: 38969985
Understanding the interplay of the proteome and the metabolome helps to understand cellular regulation and response. To enable robust inferences from such multi-omics analyses, we introduced and evaluated a workflow...
10.
Marconato L, Palla G, Yamauchi K, Virshup I, Heidari E, Treis T, et al.
Nat Methods
. 2024 Mar;
22(1):58-62.
PMID: 38509327
Spatially resolved omics technologies are transforming our understanding of biological tissues. However, the handling of uni- and multimodal spatial omics datasets remains a challenge owing to large data volumes, heterogeneity...