Wolf-Herman Fridman
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Explore the profile of Wolf-Herman Fridman including associated specialties, affiliations and a list of published articles.
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41
Citations
12762
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Recent Articles
1.
Revel M, Sautes-Fridman C, Fridman W, Roumenina L
Trends Cancer
. 2022 Mar;
8(7):517-526.
PMID: 35288093
The omics era made possible the quest for efficient markers for cancer progression and revealed that macrophage populations are much more complex than just the M1/M2 dichotomy. Complement C1q pops...
2.
Teng M, Galon J, Fridman W, Smyth M
J Clin Invest
. 2015 Aug;
125(9):3338-46.
PMID: 26241053
Cancer immunoediting explains the dual role by which the immune system can both suppress and/or promote tumor growth. Although cancer immunoediting was first demonstrated using mouse models of cancer, strong...
3.
Remark R, Becker C, Gomez J, Damotte D, Dieu-Nosjean M, Sautes-Fridman C, et al.
Am J Respir Crit Care Med
. 2014 Nov;
191(4):377-90.
PMID: 25369536
Solid tumors, beyond mere accumulation of cancer cells, form a complex ecosystem consisting of normal epithelial cells, fibroblasts, blood and lymphatic vessels, structural components, and infiltrating hematopoietic cells including myeloid...
4.
Becht E, Goc J, Germain C, Giraldo N, Dieu-Nosjean M, Sautes-Fridman C, et al.
Cancer Immunol Immunother
. 2014 Aug;
63(10):991-7.
PMID: 25112529
A high density of intratumoral effector memory CD8+/Th1 T cells is associated with favorable prognosis in most cancers and may be induced or increased by immunotherapy. Efficient adaptive immune reactions...
5.
Goc J, Fridman W, Hammond S, Sautes-Fridman C, Dieu-Nosjean M
Oncoimmunology
. 2014 Aug;
3:e28976.
PMID: 25083325
T-cell infiltrates are robust prognostic biomarkers in the majority of human cancers. However, the mechanisms that shape a protective T-cell response remain unclear. Our recent study implicates tertiary lymphoid structures...
6.
Goc J, Fridman W, Sautes-Fridman C, Dieu-Nosjean M
Oncoimmunology
. 2014 Feb;
2(12):e26836.
PMID: 24498556
Tumors are sustained by complex networks of interactions between malignant cells, stromal cells and tumor-infiltrating immune cells. These networks differ from patient to patient in terms of nature, composition and...
7.
Germain C, Gnjatic S, Tamzalit F, Knockaert S, Remark R, Goc J, et al.
Am J Respir Crit Care Med
. 2014 Feb;
189(7):832-44.
PMID: 24484236
Rationale: It is now well established that immune responses can take place outside of primary and secondary lymphoid organs. We previously described the presence of tertiary lymphoid structures (TLS) in...
8.
Goc J, Germain C, Vo-Bourgais T, Lupo A, Klein C, Knockaert S, et al.
Cancer Res
. 2013 Dec;
74(3):705-15.
PMID: 24366885
Tumor-infiltrating T cells, particularly CD45RO(+)CD8(+) memory T cells, confer a positive prognostic value in human cancers. However, the mechanisms that promote a protective T-cell response in the tumor microenvironment remain...
9.
Remark R, Alifano M, Cremer I, Lupo A, Dieu-Nosjean M, Riquet M, et al.
Clin Cancer Res
. 2013 Jun;
19(15):4079-91.
PMID: 23785047
Purpose: If immune cells are involved in tumor surveillance and have a prognostic impact in most primary tumors, little is known about their significance in metastases. Because patients' survival is...
10.
Fridman W, Dieu-Nosjean M, Pages F, Cremer I, Damotte D, Sautes-Fridman C, et al.
Cancer Microenviron
. 2012 Oct;
6(2):117-22.
PMID: 23108700
Human cancers grow in a microenvironment of stromal, inflammatory and immunocompetent cells which is variable from tumor to tumor. The characterization of the immune contexture, i.e. the type, density and...