Wing Kin Sung
Overview
Explore the profile of Wing Kin Sung including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
647
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Recent Articles
1.
Juan Tan J, Li Z, Porta M, Rajaby R, Lim W, Tan Y, et al.
Nat Commun
. 2024 Nov;
15(1):9507.
PMID: 39496583
Structural variants (SVs) are significant contributors to inter-individual genetic variation associated with traits and diseases. Current SV studies using whole-genome sequencing (WGS) have a largely Eurocentric composition, with little known...
2.
Dong P, Cai Z, Li B, Zhu Y, Chan A, Chiang M, et al.
Oncogene
. 2022 Jul;
41(36):4185-4199.
PMID: 35882980
HFE (Hemochromatosis) is a conventional iron level regulator and its loss of function due to gene mutations increases the risk of cancers including hepatocellular carcinoma (HCC). Likewise, studies focusing on...
3.
Shek F, Luo R, Lam B, Sung W, Lam T, Luk J, et al.
Cell Oncol (Dordr)
. 2017 Jun;
40(5):443-456.
PMID: 28631187
Background: Hepatocellular carcinoma (HCC) is the most common type of liver cancer worldwide. Previously, we reported that cadherin-17 (CDH17) and its related CDH17/β-catenin axis may be responsible for inducing HCC...
4.
Tennakoon C, Sung W
BMC Bioinformatics
. 2017 Apr;
18(Suppl 3):71.
PMID: 28361674
Background: The study of virus integrations in human genome is important since virus integrations were shown to be associated with diseases. In the literature, few methods have been proposed that...
5.
Kan Z, Zheng H, Liu X, Li S, Barber T, Gong Z, et al.
Genome Res
. 2013 Jun;
23(9):1422-33.
PMID: 23788652
Hepatocellular carcinoma (HCC) is one of the most deadly cancers worldwide and has no effective treatment, yet the molecular basis of hepatocarcinogenesis remains largely unknown. Here we report findings from...
6.
Sandhu K, Li G, Poh H, Quek Y, Sia Y, Peh S, et al.
Cell Rep
. 2012 Oct;
2(5):1207-19.
PMID: 23103170
Chromatin interactions play important roles in transcription regulation. To better understand the underlying evolutionary and functional constraints of these interactions, we implemented a systems approach to examine RNA polymerase-II-associated chromatin...
7.
Tan S, Lin Z, Chang C, Varang V, Chng K, Pan Y, et al.
EMBO J
. 2011 May;
30(13):2569-81.
PMID: 21572391
Oestrogen receptor α (ERα) is key player in the progression of breast cancer. Recently, the cistrome and interactome of ERα were mapped in breast cancer cells, revealing the importance of...
8.
Sheng D, Qu D, Kwok K, Ng S, Lim A, Aw S, et al.
PLoS Genet
. 2010 Apr;
6(4):e1000914.
PMID: 20421934
LRRK2 plays an important role in Parkinson's disease (PD), but its biological functions are largely unknown. Here, we cloned the homolog of human LRRK2, characterized its expression, and investigated its...
9.
Lim C, Tam W, Zhang J, Ang H, Jia H, Lipovich L, et al.
Cell Stem Cell
. 2008 Sep;
3(5):543-54.
PMID: 18804426
Stem cells self-renew or differentiate under the governance of a stem-cell-specific transcriptional program, with each transcription factor orchestrating the activities of a particular set of genes. Here we demonstrate that...
10.
Lee W, Wong C, Leong W, Miller L, Sung W
BMC Bioinformatics
. 2008 Sep;
9:368.
PMID: 18783594
Background: Pathogen detection using DNA microarrays has the potential to become a fast and comprehensive diagnostics tool. However, since pathogen detection chips currently utilize random primers rather than specific primers...