Kin Tak Chan
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Explore the profile of Kin Tak Chan including associated specialties, affiliations and a list of published articles.
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20
Citations
422
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Recent Articles
1.
Zhu Y, Lam A, Shum D, Cui D, Zhang J, Yan D, et al.
Theranostics
. 2021 Jan;
11(6):2722-2741.
PMID: 33456569
: Little is known about the roles of proteoglycans in esophageal cancer. This study aims to investigate the roles and mechanisms of serglycin (SRGN) proteoglycan in promoting metastasis of esophageal...
2.
Han L, Cui D, Li B, Xu W, Lam A, Chan K, et al.
Cancer Sci
. 2019 Oct;
110(12):3677-3688.
PMID: 31646712
5-Fluorouracil (5-FU) is a chemotherapeutic agent commonly used to treat esophageal squamous cell carcinoma (ESCC), but acquisition of chemoresistance frequently occurs and the underlying mechanisms are not fully understood. We...
3.
Li B, Hong P, Zheng C, Dai W, Chen W, Yang Q, et al.
Theranostics
. 2019 May;
9(6):1599-1613.
PMID: 31037126
Dysregulated microRNA (miRNA) expressions in cancer can contribute to chemoresistance. This study aims to identify miRNAs that are associated with fluorouracil (5-FU) chemoresistance in esophageal squamous cell carcinoma (ESCC). The...
4.
Chan C, Lai K, Ng E, Kiang M, Kwok T, Wang H, et al.
Oncol Lett
. 2018 Feb;
15(3):3273-3280.
PMID: 29435069
Esophageal squamous cell carcinoma (ESCC) is the most predominantly occurring type of esophageal cancer worldwide. Locally advanced ESCC patients are treated by neoadjuvant chemoradiation for tumor downstaging prior to tumor...
5.
Tung L, Song S, Chan K, Choi M, Lam H, Chan C, et al.
Cancer Res Treat
. 2018 Jan;
50(4):1362-1377.
PMID: 29361818
Purpose: Tumor xenograft model is an indispensable animal cancer model. In esophageal squamous cell carcinoma (ESCC) research, orthotopic tumor xenograft model establishes tumor xenograft in the animal esophagus, which allows...
6.
Chai A, Cheung A, Dai W, Ko J, Lee N, Chan K, et al.
Cancer Biomark
. 2017 Dec;
21(3):583-590.
PMID: 29278876
Background: Nidogen-2 (NID2), a secretory basement membrane protein, has been implicated as a potential biomarker in ovarian cancer and hepatocellular carcinoma. Objective: In this study, we aimed to investigate the...
7.
Shek F, Luo R, Lam B, Sung W, Lam T, Luk J, et al.
Cell Oncol (Dordr)
. 2017 Jun;
40(5):443-456.
PMID: 28631187
Background: Hepatocellular carcinoma (HCC) is the most common type of liver cancer worldwide. Previously, we reported that cadherin-17 (CDH17) and its related CDH17/β-catenin axis may be responsible for inducing HCC...
8.
Dai W, Ko J, Choi S, Yu Z, Ning L, Zheng H, et al.
J Pathol
. 2017 Jun;
242(4):500-510.
PMID: 28608921
Oesophageal squamous cell carcinoma (ESCC) is one of the most lethal cancers, owing to a high frequency of metastasis. However, little is known about the genomic landscape of metastatic ESCC....
9.
Xu W, Li B, Guan X, Chung S, Wang Y, Yip Y, et al.
Nat Commun
. 2017 Feb;
8:14399.
PMID: 28186102
Local interactions between cancer cells and stroma can produce systemic effects on distant organs to govern cancer progression. Here we show that IGF2 secreted by inhibitor of differentiation (Id1)-overexpressing oesophageal...
10.
Yu L, Kang J, Jinata C, Wang X, Wei X, Chan K, et al.
J Biomed Opt
. 2015 Dec;
20(12):126006.
PMID: 26677071
A tri-band spectroscopic optical coherence tomography (SOCT) system has been implemented for visualization of lipid and blood vessel distribution. The tri-band swept source, which covers output spectrum in 1.3, 1.5,...