Wing Hung Wong
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Explore the profile of Wing Hung Wong including associated specialties, affiliations and a list of published articles.
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105
Citations
4324
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Recent Articles
1.
Li S, Chen X, Xin J, Liu B, Liu B, Hu M, et al.
Proc Natl Acad Sci U S A
. 2025 Mar;
122(11):e2413043122.
PMID: 40067886
Stem cells possess inherent properties of self-renewal and differentiation, and thus hold significant promise for regenerating damaged tissues or replacing lost cells. Unless their therapeutic effects are solely mediated by...
2.
Gao Z, Liu Q, Zeng W, Jiang R, Wong W
Genome Biol
. 2024 Dec;
25(1):310.
PMID: 39696471
The inherent similarities between natural language and biological sequences have inspired the use of large language models in genomics, but current models struggle to incorporate chromatin interactions or predict in...
3.
Guo H, Urban A, Wong W
PLoS Genet
. 2024 Sep;
20(9):e1011412.
PMID: 39348415
Rare variants, comprising the vast majority of human genetic variations, are likely to have more deleterious impact in the context of human diseases compared to common variants. Here we present...
4.
Liu Q, Chen Z, Wong W
Proc Natl Acad Sci U S A
. 2024 May;
121(23):e2322376121.
PMID: 38809705
In this article, we develop CausalEGM, a deep learning framework for nonlinear dimension reduction and generative modeling of the dependency among covariate features affecting treatment and response. CausalEGM can be...
5.
Guo H, Urban A, Wong W
Res Sq
. 2024 May;
PMID: 38766095
Rare variants, comprising a vast majority of human genetic variations, are likely to have more deleterious impact on human diseases compared to common variants. Here we present carrier statistic, a...
6.
Stackpole M, Zeng W, Li S, Liu C, Zhou Y, He S, et al.
Nat Commun
. 2024 May;
15(1):3693.
PMID: 38693151
No abstract available.
7.
Guo H, Urban A, Wong W
bioRxiv
. 2024 Apr;
PMID: 38562756
Rare variants, comprising a vast majority of human genetic variations, are likely to have more deleterious impact on human diseases compared to common variants. Here we present carrier statistic, a...
8.
Zhu X, Ma S, Wong W
Genome Biol
. 2024 Jan;
25(1):1.
PMID: 38167462
Background: The vast majority of findings from human genome-wide association studies (GWAS) map to non-coding sequences, complicating their mechanistic interpretations and clinical translations. Non-coding sequences that are evolutionarily conserved and...
9.
Davis K, Qu P, Ma S, Lin L, Plastini M, Dahl N, et al.
Hum Mol Genet
. 2023 Aug;
32(21):3105-3120.
PMID: 37584462
DNA methyltransferase type 1 (DNMT1) is a major enzyme involved in maintaining the methylation pattern after DNA replication. Mutations in DNMT1 have been associated with autosomal dominant cerebellar ataxia, deafness...
10.
Gao Z, Liu Q, Zeng W, Jiang R, Wong W
bioRxiv
. 2023 Jul;
PMID: 37502861
The inherent similarities between natural language and biological sequences have given rise to great interest in adapting the transformer-based large language models (LLMs) underlying recent breakthroughs in natural language processing...