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Wim B van den Berg

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Articles 178
Citations 8162
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Recent Articles
1.
van den Bosch M, Ramos Y, den Hollander W, Bomer N, Nelissen R, Bovee J, et al.
Rheumatology (Oxford) . 2019 Jan; 58(6):1065-1074. PMID: 30649473
Objectives: Previously, we have shown the involvement of Wnt-activated protein Wnt-1-induced signaling protein 1 (WISP1) in the development of OA in mice. Here, we aimed to characterize the relation between...
2.
Waterborg C, Broeren M, Blaney Davidson E, Koenders M, van Lent P, van den Berg W, et al.
Rheumatology (Oxford) . 2018 Dec; 58(3):536-546. PMID: 30508140
Objective: To investigate the role of AXL, a member of the anti-inflammatory TYRO3, AXL MER (TAM) receptor family, in arthritis. Methods: KRN serum transfer arthritis was induced in Axl-/- and...
3.
Broeren M, Di Ceglie I, Bennink M, van Lent P, van den Berg W, Koenders M, et al.
PeerJ . 2018 Jun; 6:e4771. PMID: 29868252
Objective: Tumor necrosis factor-inducible gene 6 (TSG-6) has anti-inflammatory and chondroprotective effects in mouse models of inflammatory arthritis. Because cartilage damage and inflammation are also observed in osteoarthritis (OA), we...
4.
Waterborg C, Beermann S, Broeren M, Bennink M, Koenders M, van Lent P, et al.
Front Immunol . 2018 May; 9:742. PMID: 29706963
Objective: Rheumatoid arthritis (RA) is a chronic and progressive joint disease. It appears that anti-inflammatory feedback mechanisms that could restrain joint inflammation and restore homeostasis are insufficient to perform this...
5.
van der Geest T, Roeleveld D, Walgreen B, Helsen M, Nayak T, Klein C, et al.
Rheumatology (Oxford) . 2018 Jan; 57(4):737-747. PMID: 29361119
Objectives: RA is a chronic autoimmune disease leading to progressive destruction of cartilage and bone. RA patients show elevated IL-22 levels and the amount of IL-22-producing Th cells positively correlates...
6.
Rogier R, Evans-Marin H, Manasson J, van der Kraan P, Walgreen B, Helsen M, et al.
Sci Rep . 2017 Nov; 7(1):15613. PMID: 29142301
Perturbations of the intestinal microbiome have been observed in patients with new-onset and chronic autoimmune inflammatory arthritis. However, it is currently unknown whether these alterations precede the development of arthritis...
7.
van den Bosch M, Blom A, van de Loo F, Koenders M, Lafeber F, van den Berg W, et al.
Arthritis Rheumatol . 2017 Jul; 69(10):1978-1983. PMID: 28678406
Objective: Increased Wnt signaling in chondrocytes is associated with development of osteoarthritis (OA). However, OA is considered a disease of the entire joint, where the synovium has been attributed an...
8.
Rogier R, Ederveen T, Boekhorst J, Wopereis H, Scher J, Manasson J, et al.
Microbiome . 2017 Jun; 5(1):63. PMID: 28645307
Background: Perturbation of commensal intestinal microbiota has been associated with several autoimmune diseases. Mice deficient in interleukin-1 receptor antagonist (Il1rn mice) spontaneously develop autoimmune arthritis and are susceptible to other...
9.
Roeleveld D, Marijnissen R, Walgreen B, Helsen M, van den Bersselaar L, van de Loo F, et al.
PLoS One . 2017 Feb; 12(2):e0171757. PMID: 28158305
Th17 cells and their cytokines are linked to the pathogenesis of rheumatoid arthritis, a chronic autoimmune disease characterized by joint inflammation. Th17 development is initiated by combined signaling of TGF-β...
10.
Broeren M, de Vries M, Bennink M, Arntz O, van Lent P, van der Kraan P, et al.
Arthritis Res Ther . 2016 Aug; 18:186. PMID: 27519904
Background: Gene therapy has the potential to provide long-term production of therapeutic proteins in the joints of osteoarthritis (OA) patients. The objective of this study was to analyse the therapeutic...