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Wim B van den Berg

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Articles 178
Citations 8162
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Recent Articles
11.
van den Bosch M, Blom A, Schelbergen R, Koenders M, van de Loo F, van den Berg W, et al.
J Rheumatol . 2016 Aug; 43(10):1874-1884. PMID: 27481901
Objective: The alarmins S100A8 and S100A9 have been shown to regulate synovial activation, cartilage damage, and osteophyte formation in osteoarthritis (OA). Here we investigated the effect of S100A9 on the...
12.
Koenders M, van den Berg W
Drug Des Devel Ther . 2016 Jul; 10:2069-80. PMID: 27445458
Rheumatic disease is not a single disorder, but a group of more than 100 diseases that affect joints, connective tissues, and/or internal organs. Although rheumatic diseases like rheumatoid arthritis (RA),...
13.
Oliveira M, Di Ceglie I, Arntz O, van den Berg W, van den Hoogen F, Ferreira A, et al.
J Cell Physiol . 2016 May; 232(1):225-33. PMID: 27138291
The general consensus is that milk promotes bone growth and density because is a source of calcium and contains components that enhance intestinal calcium uptake or directly affect bone metabolism....
14.
Oliveira M, Arntz O, Blaney Davidson E, van Lent P, Koenders M, van der Kraan P, et al.
J Nutr Biochem . 2016 Mar; 30:74-84. PMID: 27012623
The claimed beneficial effect of milk on bone is still a matter for debate. Recently extracellular vesicles (EVs) that contain proteins and RNA were discovered in milk, but their effect...
15.
Broeren M, de Vries M, Bennink M, Arntz O, Blom A, Koenders M, et al.
Hum Gene Ther . 2015 Dec; 27(3):244-54. PMID: 26711533
Disease-inducible promoters for the treatment of rheumatoid arthritis (RA) have the potential to provide regulated expression of therapeutic proteins in arthritic joints. In this study, we set out to identify...
16.
van den Bosch M, Gleissl T, Blom A, van den Berg W, van Lent P, van der Kraan P
Rheumatology (Oxford) . 2015 Dec; 55(9):1536-47. PMID: 26667213
The Wnt signalling pathway is gaining increasing attention in the field of joint pathologies, attributable to its role in the development and homeostasis of the tissues found in the joint,...
17.
Santegoets K, Wenink M, Vieira Braga F, Cossu M, Lamers-Karnebeek F, van Riel P, et al.
Arthritis Rheumatol . 2015 Nov; 68(4):795-804. PMID: 26606260
Objective: The prevalence of periodontitis is increased in patients with rheumatoid arthritis (RA), and the severity of periodontitis can affect the level of arthritis. Porphyromonas gingivalis is one of the...
18.
van den Bosch M, Blom A, Schelbergen R, Vogl T, Roth J, Sloetjes A, et al.
Arthritis Rheumatol . 2015 Sep; 68(1):152-63. PMID: 26360647
Objective: Both alarmins S100A8/A9 and canonical Wnt signaling have been found to play active roles in the development of experimental osteoarthritis (OA). However, what activates canonical Wnt signaling remains unknown....
19.
Bluml S, Sahin E, Saferding V, Goncalves-Alves E, Hainzl E, Niederreiter B, et al.
Arthritis Res Ther . 2015 Aug; 17:230. PMID: 26307404
Introduction: Autoreactive T cells are a central element in many systemic autoimmune diseases. The generation of these pathogenic T cells is instructed by antigen-presenting cells (APCs). However, signaling pathways in...
20.
de Munter W, van der Kraan P, van den Berg W, van Lent P
Rheumatology (Oxford) . 2015 Aug; 55(1):16-24. PMID: 26231344
There is increasing evidence that low-density lipoprotein (LDL) cholesterol plays a role in the pathology of OA. Specifically, oxidized LDL (oxLDL), which has been shown to play an essential role...