William M Schneider
Overview
Explore the profile of William M Schneider including associated specialties, affiliations and a list of published articles.
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41
Citations
4751
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Recent Articles
1.
Block T, Guo J, Zoulim F, Rice C, Thio C, Schneider W, et al.
Nat Rev Gastroenterol Hepatol
. 2025 Feb;
22(3):150-151.
PMID: 39910374
No abstract available.
2.
Le Pen J, Paniccia G, Kinast V, Moncada-Velez M, Ashbrook A, Bauer M, et al.
PLoS Biol
. 2024 Sep;
22(9):e3002767.
PMID: 39316623
Interferons (IFNs) play a crucial role in the regulation and evolution of host-virus interactions. Here, we conducted a genome-wide arrayed CRISPR knockout screen in the presence and absence of IFN...
3.
Cattle M, Aguado L, Sze S, Wang D, Papagiannakopoulos T, Smith S, et al.
bioRxiv
. 2024 Aug;
PMID: 39149392
Retrons are a retroelement class found in diverse prokaryotes that can be adapted to augment CRISPR-Cas9 genome engineering technology to efficiently rewrite short stretches of genetic information in bacteria and...
4.
Yu Y, Kass M, Zhang M, Youssef N, Freije C, Brock K, et al.
Cell
. 2024 May;
187(11):2735-2745.e12.
PMID: 38723628
Hepatitis B virus (HBV) is a small double-stranded DNA virus that chronically infects 296 million people. Over half of its compact genome encodes proteins in two overlapping reading frames, and...
5.
Yu Y, Schneider W, Kass M, Michailidis E, Acevedo A, Pamplona Mosimann A, et al.
Sci Adv
. 2023 Apr;
9(15):eadg6265.
PMID: 37043562
Hepatitis B virus (HBV) chronically infects an estimated 300 million people, and standard treatments are rarely curative. Infection increases the risk of liver cirrhosis and hepatocellular carcinoma, and consequently, nearly...
6.
Sadic M, Schneider W, Katsara O, Medina G, Fisher A, Mogulothu A, et al.
EMBO Rep
. 2022 Oct;
23(12):e55218.
PMID: 36256515
Co-opting host cell protein synthesis is a hallmark of many virus infections. In response, certain host defense proteins limit mRNA translation globally, albeit at the cost of the host cell's...
7.
Kabbani M, Michailidis E, Steensels S, Fulmer C, Luna J, Le Pen J, et al.
Cell Rep
. 2022 Sep;
40(11):111321.
PMID: 36103835
Advanced non-alcoholic fatty liver disease (NAFLD) is a rapidly emerging global health problem associated with pre-disposing genetic polymorphisms, most strikingly an isoleucine to methionine substitution in patatin-like phospholipase domain-containing protein...
8.
Schneider W, Hoffmann H
Curr Opin Virol
. 2021 Dec;
52:71-77.
PMID: 34896863
Flaviviruses are zoonotic pathogens transmitted by the bite of infected mosquitos and ticks and represent a constant burden to human health. Here we review recent literature aimed at uncovering how...
9.
Luu A, Yao Z, Ramachandran S, Azzopardi S, Miles L, Schneider W, et al.
Viruses
. 2021 Nov;
13(11).
PMID: 34834920
Zika virus (ZIKV) is a re-emerging flavivirus that has caused large-scale epidemics. Infection during pregnancy can lead to neurologic developmental abnormalities in children. There is no approved vaccine or therapy...
10.
Ricardo-Lax I, Luna J, Thao T, Le Pen J, Yu Y, Hoffmann H, et al.
Science
. 2021 Oct;
374(6571):1099-1106.
PMID: 34648371
Molecular virology tools are critical for basic studies of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and for developing new therapeutics. Experimental systems that do not rely on viruses...