William M Nauseef
Overview
Explore the profile of William M Nauseef including associated specialties, affiliations and a list of published articles.
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118
Citations
5697
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Recent Articles
1.
Knaus U, Clark R, Nauseef W, Dinauer M, Leto T, Jaquet V
Immunity
. 2024 Aug;
57(8):1716-1718.
PMID: 39142268
No abstract available.
2.
Jennings S, Hu Y, Wellems D, Luo M, Scull C, Taylor C, et al.
J Leukoc Biol
. 2023 Mar;
113(6):604-614.
PMID: 36976023
Cystic fibrosis is a life-threatening genetic disorder caused by mutations in the CFTR chloride channel. Clinically, over 90% of patients with cystic fibrosis succumb to pulmonary complications precipitated by chronic...
3.
4.
Das Gupta K, Ramnath D, von Pein J, Curson J, Wang Y, Abrol R, et al.
Proc Natl Acad Sci U S A
. 2023 Jan;
120(4):e2212813120.
PMID: 36649417
The immune system must be able to respond to a myriad of different threats, each requiring a distinct type of response. Here, we demonstrate that the cytoplasmic lysine deacetylase HDAC7...
5.
Nauseef W
Immunol Rev
. 2022 Nov;
314(1):442-456.
PMID: 36380497
Human and murine neutrophils differ with respect to representation in blood, receptors, nuclear morphology, signaling pathways, granule proteins, NADPH oxidase regulation, magnitude of oxidant and hypochlorous acid production, and their...
6.
Nauseef W
J Leukoc Biol
. 2022 Aug;
112(4):587-589.
PMID: 35929044
The text extracted from the initial paragraph of a paper coauthored by Zanvil Cohn, one of the pioneers in the study of leukocyte biology, highlights two phenomena that stimulated investigations...
7.
Wang G, Nauseef W
Blood
. 2022 Feb;
139(17):2622-2631.
PMID: 35213685
Polymorphonuclear neutrophils (PMNs) figure prominently in host defense against infection and in noninfectious inflammation. Mobilized early in an inflammatory response, PMNs mediate immediate cellular defense against microbes and orchestrate events...
8.
Amjadi M, Avner B, Greenlee-Wacker M, Horswill A, Nauseef W
J Leukoc Biol
. 2021 Mar;
110(5):917-925.
PMID: 33682200
Neutrophils (PMN) regulate inflammation in many ways, including communication with other immune cells via extracellular vesicles (EVs). EVs released by human neutrophils activated with N-formylmethionyl-leucyl-phenylalanine (fMLF) (PMN-fMLF EVs) had an...
9.
Kavanaugh J, Leidal K, Nauseef W, Horswill A
J Infect Dis
. 2020 Sep;
223(11):1865-1869.
PMID: 32995850
Polymorphonuclear leukocytes (PMN) phagocytose and kill individual bacteria but are far less efficient when challenged with bacterial aggregates. Consequently, growth within a biofilm affords Staphylococcus aureus some protection but PMN...
10.
Cho C, Teghanemt A, Apicella M, Nauseef W
J Leukoc Biol
. 2020 Sep;
108(5):1543-1553.
PMID: 32977356
Optimal innate immune response to infection includes eradication of potential pathogens, resolution of associated inflammation, and restitution of homeostasis. Phagocytosing human polymorphonuclear leukocytes (hPMN) undergo accelerated apoptosis, a process referred...