William Hallett
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Explore the profile of William Hallett including associated specialties, affiliations and a list of published articles.
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14
Citations
385
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Recent Articles
1.
Ribeiro D, Hallett W, Howes O, McCutcheon R, Nour M, Tavares A
EJNMMI Res
. 2022 Feb;
12(1):11.
PMID: 35184229
Introduction: Q.Clear is a Bayesian penalised likelihood (BPL) reconstruction algorithm available on General Electric (GE) Positron Emission Tomography (PET)-Computed Tomography (CT) and PET-Magnetic Resonance (MR) scanners. This algorithm is regulated...
2.
Myler H, Pedras-Vasconcelos J, Phillips K, Hottenstein C, Chamberlain P, Devanaryan V, et al.
AAPS J
. 2021 Dec;
24(1):4.
PMID: 34853961
Evolving immunogenicity assay performance expectations and a lack of harmonized anti-drug antibody validation testing and reporting tools have resulted in significant time spent by health authorities and sponsors on resolving...
3.
Ji P, Ren Y, Li L, Schrieber S, Pisal D, Hallett W, et al.
J Clin Pharmacol
. 2021 Aug;
62(1):36-45.
PMID: 34411322
The risk in terms of safety or diminished efficacy of switching between an originator biological product and a proposed interchangeable product is an important consideration for interchangeability evaluation in the...
4.
McCutcheon R, Brown K, Nour M, Smith S, Veronese M, Zelaya F, et al.
Sci Adv
. 2021 Jun;
7(24).
PMID: 34108214
Dopamine signaling is constrained to discrete tracts yet has brain-wide effects on neural activity. The nature of this relationship between local dopamine signaling and brain-wide neuronal activity is not clearly...
5.
Ribeiro D, Hallett W, Tavares A
EJNMMI Phys
. 2021 May;
8(1):41.
PMID: 33961164
Background: Q.Clear is a Bayesian penalized likelihood (BPL) reconstruction algorithm that presents improvements in signal-to-noise ratio (SNR) in clinical positron emission tomography (PET) scans. Brain studies in research require a...
6.
Wadhwa P, Thielemans K, Efthimiou N, Wangerin K, Keat N, Emond E, et al.
Methods
. 2020 Feb;
185:110-119.
PMID: 32006678
This work demonstrates how computational and physical modelling of the positron emission tomography (PET) image acquisition process for a state-of-the-art integrated PET and magnetic resonance imaging (PET-MR) system can produce...
7.
Jing X, Hou Y, Hallett W, Sahajwalla C, Ji P
Adv Exp Med Biol
. 2019 Sep;
1148:115-129.
PMID: 31482497
Therapeutic proteins are a rapidly growing class of drugs in clinical settings. The pharmacokinetics (PK) of therapeutic proteins relies on their absorption, distribution, metabolism, and excretion (ADME) properties. Moreover, the...
8.
Akerele M, Wadhwa P, Silva-Rodriguez J, Hallett W, Tsoumpas C
EJNMMI Phys
. 2018 Dec;
5(1):34.
PMID: 30519974
Background: Positron emission tomography (PET) imaging has a wide applicability in oncology, cardiology and neurology. However, a major drawback when imaging very active regions such as the bladder is the...
9.
Chen J, Bozza W, Di X, Zhang Y, Hallett W, Zhang B
Oncotarget
. 2014 Jul;
5(13):5125-37.
PMID: 25026275
TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis through the death receptors (DRs) 4 and/or 5 expressed on the cell surface. Multiple clinical trials are underway to evaluate the antitumor activity of...
10.
Comley R, Salinas C, Mizrahi R, Vitcu I, Ng A, Hallett W, et al.
Mol Imaging Biol
. 2011 Nov;
14(4):517-21.
PMID: 22076076
Purpose: We measured the whole-body distribution of IV-injected [¹¹C]GSK215083, a new 5-HT₆ antagonist PET tracer, as a function of time in adult subjects, in order to determine the radiation exposure....