William D Shannon
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Explore the profile of William D Shannon including associated specialties, affiliations and a list of published articles.
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51
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Recent Articles
1.
Blount K, Papazyan R, Ferdyan N, Srinivasan K, Gonzalez C, Shannon W, et al.
J Infect Dis
. 2024 Aug;
PMID: 39172632
Background: Microbiota-based treatments are effective in preventing recurrent Clostridioides difficile infection (rCDI). Fecal microbiota, live-jslm (REBYOTA®; RBL, previously RBX2660) was shown to prevent rCDI in a phase 3, randomized, double-blinded...
2.
Sahu U, Villa E, Reczek C, Zhao Z, OHara B, Torno M, et al.
Science
. 2024 Mar;
383(6690):1484-1492.
PMID: 38547260
Cellular purines, particularly adenosine 5'-triphosphate (ATP), fuel many metabolic reactions, but less is known about the direct effects of pyrimidines on cellular metabolism. We found that pyrimidines, but not purines,...
3.
Kocharovsky V, Kocharovsky V, Shannon W, Tarasov S
Entropy (Basel)
. 2023 Dec;
25(12).
PMID: 38136464
We describe boson sampling of interacting atoms from the noncondensed fraction of Bose-Einstein-condensed (BEC) gas confined in a box trap as a new platform for studying computational ♯P-hardness and quantum...
4.
Papazyan R, Ferdyan N, Srinivasan K, Gonzalez C, Shannon W, Blount K, et al.
Microorganisms
. 2023 Jan;
11(1).
PMID: 36677428
Microbiome-based therapeutics are increasingly evaluated as a strategy to reduce recurrent infection (rCDI), with proposed mechanisms including restoration of the microbiota and microbiota-mediated functions, such as bile acid (BA) metabolism....
5.
Blount K, Jones C, Walsh D, Gonzalez C, Shannon W
Front Microbiol
. 2022 Jan;
12:781275.
PMID: 35058900
The human gut microbiota are important to health and wellness, and disrupted microbiota homeostasis, or "dysbiosis," can cause or contribute to many gastrointestinal disease states. Dysbiosis can be caused by...
6.
Khanna S, Pardi D, Jones C, Shannon W, Gonzalez C, Blount K
Clin Infect Dis
. 2020 Sep;
73(7):e1613-e1620.
PMID: 32966574
Background: Recurrent Clostridioides difficile infections (rCDI) are a global public health threat. To reduce rCDI, microbiota-restoring therapies are needed, particularly standardized, easy-to-administer formulations. Methods: This phase I open-label trial assessed...
7.
Yang D, Johnson J, Zhou X, Deych E, Shands B, Hanson B, et al.
Sci Rep
. 2019 Dec;
9(1):20082.
PMID: 31882682
Regressing an outcome or dependent variable onto a set of input or independent variables allows the analyst to measure associations between the two so that changes in the outcome can...
8.
Blount K, Shannon W, Deych E, Jones C
Open Forum Infect Dis
. 2019 Apr;
6(4):ofz095.
PMID: 31024971
Background: RBX2660 is an investigational microbiota restoration therapy in phase 3 clinical development for preventing recurrent infections (CDIs). In a randomized, double-blinded placebo-controlled phase 2B trial, RBX2660 was effective at...
9.
Barron L, Warner B, Tarr P, Shannon W, Deych E, Warner B
J Pediatr Surg
. 2017 Apr;
52(6):993-998.
PMID: 28410788
Introduction: Necrotizing enterocolitis (NEC) is a common and devastating gastrointestinal disease of premature infants. NEC severity varies widely. Recent data have demonstrated a strong link between gut microbial dysbiosis and...
10.
Horner C, Dula C, Bacharier L, Garbutt J, Gonzalez C, Deych E, et al.
J Allergy Clin Immunol
. 2016 Jun;
138(4):1196-1199.e3.
PMID: 27246525
No abstract available.