William C Merrick
Overview
Explore the profile of William C Merrick including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
61
Citations
3743
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
21.
Komar A, Mazumder B, Merrick W
Gene
. 2012 May;
502(2):75-86.
PMID: 22555019
Studies over the past 5 or so years have indicated that the traditional clustering of mechanisms for translation initiation in eukaryotes into cap-dependent and cap-independent (or IRES-mediated) is far too...
22.
Reineke L, Cao Y, Baus D, Hossain N, Merrick W
PLoS One
. 2011 Sep;
6(9):e24492.
PMID: 21915340
Eukaryotic initiation factor 2A is a single polypeptide that acts to negatively regulate IRES-mediated translation during normal cellular conditions. We have found that eIF2A (encoded by YGR054w) abundance is reduced...
23.
Krokowski D, Gaccioli F, Majumder M, Mullins M, Yuan C, Papadopoulou B, et al.
Cell Cycle
. 2011 Jul;
10(16):2691-702.
PMID: 21768774
Protein synthesis across kingdoms involves the assembly of 70S (prokaryotes) or 80S (eukaryotes) ribosomes on the mRNAs to be translated. 70S ribosomes are protected from degradation in bacteria during stationary...
24.
Parsyan A, Svitkin Y, Shahbazian D, Gkogkas C, Lasko P, Merrick W, et al.
Nat Rev Mol Cell Biol
. 2011 Mar;
12(4):235-45.
PMID: 21427765
The translation initiation step in eukaryotes is highly regulated and rate-limiting. During this process, the 40S ribosomal subunit is usually recruited to the 5' terminus of the mRNA. It then...
25.
Hussey G, Chaudhury A, Dawson A, Lindner D, Knudsen C, Wilce M, et al.
Mol Cell
. 2011 Feb;
41(4):419-31.
PMID: 21329880
Transcript-selective translational regulation of epithelial-mesenchymal transition (EMT) by transforming growth factor-β (TGF-β) is directed by the hnRNP E1-containing TGF-β-activated-translational (BAT) mRNP complex. Herein, eukaryotic elongation factor-1 A1 (eEF1A1) is identified...
26.
Dmitriev S, Terenin I, Andreev D, Ivanov P, Dunaevsky J, Merrick W, et al.
J Biol Chem
. 2010 Jun;
285(35):26779-26787.
PMID: 20566627
During translation, aminoacyl-tRNAs are delivered to the ribosome by specialized GTPases called translation factors. Here, we report the tRNA binding to the P-site of 40 S ribosomes by a novel...
27.
28.
29.
Schneider-Poetsch T, Ju J, Eyler D, Dang Y, Bhat S, Merrick W, et al.
Nat Chem Biol
. 2010 Feb;
6(3):209-217.
PMID: 20118940
Although the protein synthesis inhibitor cycloheximide (CHX) has been known for decades, its precise mechanism of action remains incompletely understood. The glutarimide portion of CHX is seen in a family...
30.
Reineke L, Merrick W
RNA
. 2009 Oct;
15(12):2264-77.
PMID: 19861427
Cap-independent initiation of translation is thought to promote protein synthesis on some mRNAs during times when cap-dependent initiation is down-regulated. However, the mechanism of cap-independent initiation is poorly understood. We...