Wenji Piao
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Explore the profile of Wenji Piao including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
1024
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Recent Articles
11.
Saxena V, Piao W, Li L, Paluskievicz C, Xiong Y, Simon T, et al.
Cell Rep
. 2022 Apr;
39(3):110727.
PMID: 35443187
Regulatory T cell (Treg) lymphatic migration is required for resolving inflammation and prolonging allograft survival. Focusing on Treg interactions with lymphatic endothelial cells (LECs), we dissect mechanisms and functional consequences...
12.
Piao W, Kasinath V, Saxena V, Lakhan R, Iyyathurai J, Bromberg J
Cells
. 2021 Apr;
10(4).
PMID: 33805271
The pleiotropic functions of lymphotoxin (LT)β receptor (LTβR) signaling are linked to the control of secondary lymphoid organ development and structural maintenance, inflammatory or autoimmune disorders, and carcinogenesis. Recently, LTβR...
13.
Lee Y, Zhang T, Saxena V, Li L, Piao W, Bromberg J, et al.
Am J Transplant
. 2020 Apr;
20(9):2343-2355.
PMID: 32282980
Myeloid-derived suppressor cells (MDSCs) expand in an inflammatory microenvironment such as cancer and autoimmunity. To study if transplantation induces MDSCs and these cells regulate allograft survival, C57BL/6 donor hearts were...
14.
Li L, Shirkey M, Zhang T, Xiong Y, Piao W, Saxena V, et al.
J Clin Invest
. 2020 Feb;
130(5):2602-2619.
PMID: 32017712
Lymph node stromal cells (LNSCs) regulate immunity through constructing lymphocyte niches. LNSC-produced laminin α5 (Lama5) regulates CD4+ T cells but the underlying mechanisms of its functions are poorly understood. Here...
15.
Piao W, Xiong Y, Li L, Saxena V, Smith K, Hippen K, et al.
Cell Rep
. 2020 Jan;
30(4):1052-1062.e5.
PMID: 31995749
Regulatory T cells (Tregs) express high levels of cell surface lymphotoxin alpha beta (LTα1β2) to activate the LT beta receptor (LTβR) on the lymphatic endothelial cells (LECs), modulating LEC adhesion...
16.
Piao W, Xiong Y, Famulski K, Brinkman C, Li L, Toney N, et al.
Nat Commun
. 2019 Jun;
10(1):2927.
PMID: 31249309
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
17.
Hisano Y, Kono M, Cartier A, Engelbrecht E, Kano K, Kawakami K, et al.
J Exp Med
. 2019 Jun;
216(7):1582-1598.
PMID: 31147448
Sphingosine 1-phosphate (S1P) and lysophosphatidic acid (LPA) activate G protein-coupled receptors (GPCRs) to regulate biological processes. Using a genome-wide CRISPR/dCas9-based GPCR signaling screen, LPAR1 was identified as an inducer of...
18.
Xiong Y, Piao W, Brinkman C, Li L, Kulinski J, Olivera A, et al.
Sci Immunol
. 2019 Mar;
4(33).
PMID: 30877143
Sphingosine 1-phosphate (S1P) and S1P receptors (S1PRs) regulate migration of lymphocytes out of thymus to blood and lymph nodes (LNs) to efferent lymph, whereas their role in other tissue sites...
19.
Piao W, Xiong Y, Famulski K, Brinkman C, Li L, Toney N, et al.
Nat Commun
. 2018 Aug;
9(1):3020.
PMID: 30069025
Lymphotoxin-beta receptor (LTβR) signaling in lymphatic endothelial cells (LEC) regulates leukocyte afferent lymphatic transendothelial migration (TEM). The function of individual signaling pathways for different leukocyte subsets is currently unknown. Here,...
20.
Piao W, Ru L, Toshchakov V
Pathog Dis
. 2016 May;
74(5).
PMID: 27150837
TLR2 heterodimers with TLR1 or TLR6 recognize distinct pathogen-associated molecules such as tri- and di-acylated lipopeptides. The activated TLR2 heterodimers recruit Toll-IL-1R domain- (TIR-) containing adapter proteins, TIRAP and MyD88,...