Wen-Pin Yang
Overview
Explore the profile of Wen-Pin Yang including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
1403
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Recent Articles
1.
Zepp J, Zhao J, Liu C, Bulek K, Wu L, Chen X, et al.
J Immunol
. 2017 Oct;
199(11):3849-3857.
PMID: 29070673
This study identifies a novel mechanism linking IL-17A with colon tissue repair and tumor development. Abrogation of IL-17A signaling in mice attenuated tissue repair of dextran sulfate sodium (DSS)-induced damage...
2.
Dudhgaonkar S, Ranade S, Nagar J, Subramani S, Prasad D, Karunanithi P, et al.
J Immunol
. 2016 Dec;
198(3):1308-1319.
PMID: 28003376
The serine/threonine kinase IL-1R-associated kinase (IRAK)4 is a critical regulator of innate immunity. We have identified BMS-986126, a potent, highly selective inhibitor of IRAK4 kinase activity that demonstrates equipotent activity...
3.
Parks B, Sallam T, Mehrabian M, Psychogios N, Hui S, Norheim F, et al.
Cell Metab
. 2015 Feb;
21(2):334-347.
PMID: 25651185
Insulin resistance (IR) is a complex trait with multiple genetic and environmental components. Confounded by large differences between the sexes, environment, and disease pathology, the genetic basis of IR has...
4.
Ghazalpour A, Bennett B, Shih D, Che N, Orozco L, Pan C, et al.
Mol Syst Biol
. 2014 May;
10:730.
PMID: 24860088
We profiled and analyzed 283 metabolites representing eight major classes of molecules including Lipids, Carbohydrates, Amino Acids, Peptides, Xenobiotics, Vitamins and Cofactors, Energy Metabolism, and Nucleotides in mouse liver of...
5.
Erbilgin A, Siemers N, Kayne P, Yang W, Berliner J, Lusis A
Arterioscler Thromb Vasc Biol
. 2013 Aug;
33(11):2509-17.
PMID: 23990205
Objective: Endothelial cells are central to the initiation of atherosclerosis, yet there has been limited success in studying their gene expression in the mouse aorta. To address this, we developed...
6.
Herjan T, Yao P, Qian W, Li X, Liu C, Bulek K, et al.
J Immunol
. 2013 Jun;
191(2):640-9.
PMID: 23772036
IL-17, a major inflammatory cytokine plays a critical role in the pathogenesis of many autoimmune inflammatory diseases. In this study, we report a new function of RNA-binding protein HuR in...
7.
Civelek M, Hagopian R, Pan C, Che N, Yang W, Kayne P, et al.
Hum Mol Genet
. 2013 Apr;
22(15):3023-37.
PMID: 23562819
The genetics of messenger RNA (mRNA) expression has been extensively studied in humans and other organisms, but little is known about genetic factors contributing to microRNA (miRNA) expression. We examined...
8.
Garcia R, Search D, Lupisella J, Ostrowski J, Guan B, Chen J, et al.
PLoS One
. 2013 Feb;
8(2):e53192.
PMID: 23383297
Background: Chronic glucocorticoid excess has been linked to increased atherosclerosis and general cardiovascular risk in humans. The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) increases active glucocorticoid levels within tissues by...
9.
Roongta U, Pabalan J, Wang X, Ryseck R, Fargnoli J, Henley B, et al.
Mol Cancer Res
. 2011 Sep;
9(11):1551-61.
PMID: 21954435
Emerging literature suggests that metabolic pathways play an important role in the maintenance and progression of human cancers. In particular, recent studies have implicated lipid biosynthesis and desaturation as a...
10.
Romanoski C, Che N, Yin F, Mai N, Pouldar D, Civelek M, et al.
Circ Res
. 2011 Jul;
109(5):e27-41.
PMID: 21737788
Rationale: Oxidized palmitoyl arachidonyl phosphatidylcholine (Ox-PAPC) accumulates in atherosclerotic lesions, is proatherogenic, and influences the expression of more than 1000 genes in endothelial cells. Objective: To elucidate the major pathways...