Wen-Chung Chen
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Explore the profile of Wen-Chung Chen including associated specialties, affiliations and a list of published articles.
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28
Citations
378
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Recent Articles
11.
Liu Y, Tsai Y, Lin S, Liao N, Jan M, Liang C, et al.
Sci Rep
. 2016 May;
6:26646.
PMID: 27221351
PPARγ modulates energy metabolism and inflammation. However, its specific functions in the balance of immunity in vivo have been explored incompletely. In this study, by the age of 14 mo,...
12.
Integrin-linked kinase as a novel molecular switch of the IL-6-NF-κB signaling loop in breast cancer
Hsu E, Kulp S, Huang H, Tu H, Chao M, Tseng Y, et al.
Carcinogenesis
. 2016 Feb;
37(4):430-442.
PMID: 26905583
Substantial evidence has clearly demonstrated the role of the IL-6-NF-κB signaling loop in promoting aggressive phenotypes in breast cancer. However, the exact mechanism by which this inflammatory loop is regulated...
13.
Jheng H, Tsai P, Chuang Y, Shen Y, Tai T, Chen W, et al.
Dis Model Mech
. 2015 Sep;
8(10):1311-21.
PMID: 26398934
Increased urinary albumin excretion is not simply an aftermath of glomerular injury, but is also involved in the progression of diabetic nephropathy (DN). Whereas Toll-like receptors (TLRs) are incriminated in...
14.
Chen H, Chen W, Liang Z, Tsai W, Long Y, Aiba I, et al.
Expert Opin Ther Targets
. 2015 May;
19(10):1307-17.
PMID: 26004625
Introduction: Platinum (Pt)-based antitumor agents remain important chemotherapeutic agents for treating many human malignancies. Elevated expression of the human high-affinity copper transporter 1 (hCtr1), resulting in enhanced Pt drug transport...
15.
Tsai H, Song H, Chen W, Chang C, Chang C, Lee I
Taiwan J Obstet Gynecol
. 2013 Oct;
52(3):411-4.
PMID: 24075383
Objective: Spontaneous delayed uterine rupture is life-threatening and extremely rare following sexual intercourse in postpartum. Here, we present a case of delayed uterine rupture that occurred 4 weeks after cesarean...
16.
Chen C, Chen W, Peng S, Huang S
J Formos Med Assoc
. 2013 Jun;
112(6):358-62.
PMID: 23787013
Diffuse sclerosing papillary thyroid carcinoma (DSPTC) is a relatively rare variant of papillary thyroid carcinoma with distinct histological features, radiological characteristics, and biological aggressiveness. Compared with conventional papillary thyroid carcinoma,...
17.
Chen W, Lai Y, Chen H, Guo H, Su I, Chen H
Histopathology
. 2013 Jun;
63(2):225-33.
PMID: 23738752
Aims: Interleukin-17 (IL-17) is a proinflammatory cytokine that is most prominently produced by T-helper type 17 (Th17) cells, a distinct CD4+ T-helper cell subset. The aim of this study was...
18.
Kuo Y, Chen W, Yao W, Cheng L, Hsu H, Lai H, et al.
Int J Surg
. 2013 May;
11(7):538-43.
PMID: 23707626
Background: Current guidelines for breast cancer treatment recommend completion axillary lymph node dissection (CALND) following in case of positive sentinel lymph node (SLN) metastasis, which only in 35%-70% shows additional...
19.
Chen C, Liou S, Chen C, Chen W, Hu F, Wang I, et al.
J Biol Chem
. 2013 Feb;
288(17):11689-704.
PMID: 23430247
Recent studies indicate that caspase-2 is involved in the early stages of apoptosis, particularly before the occurrence of mitochondrial damage. Here we report the important role of the coenzyme Q10...
20.
Chen H, Yan J, Chen W, Kuo M, Lai Y, Lai W, et al.
Lung Cancer
. 2011 Jul;
75(2):228-34.
PMID: 21788094
Background: Recent studies have shown that human copper transporter 1 (hCtr1), the major copper influx transporter, is involved in the transport of platinum-based antitumor agents. We investigated the predictive and...