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Weiming Xia

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Articles 135
Citations 3570
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Recent Articles
1.
Safi A, Giunti E, Melikechi O, Xia W, Melikechi N
Heliyon . 2025 Feb; 11(3):e42349. PMID: 39981365
Early detection of Alzheimer's disease is essential for effective treatment and the development of therapies that modify disease progression. Developing sensitive and specific noninvasive diagnostic tools is crucial for improving...
2.
Nicks R, Shah A, Stathas S, Kirsch D, Horowitz S, Saltiel N, et al.
Acta Neuropathol . 2024 Dec; 148(1):79. PMID: 39643767
Neurodegeneration is a seminal feature of many neurological disorders. Chronic traumatic encephalopathy (CTE) is caused by repetitive head impacts (RHI) and is characterized by sulcal tau pathology. However, quantitative assessments...
3.
Yeganeh P, Kwak S, Jorfi M, Koler K, Kalatturu T, von Maydell D, et al.
Neuron . 2024 Nov; 113(2):205-224.e8. PMID: 39610246
Alzheimer's disease (AD) presents a complex pathological landscape, posing challenges to current therapeutic strategies that primarily target amyloid-β (Aβ). Using a novel integrative pathway activity analysis (IPAA), we identified 83...
4.
Collu R, Zarate Y, Xia W, Fish J
Metab Brain Dis . 2024 Nov; 40(1):3. PMID: 39541055
Special AT-rich sequence-binding protein 2 (SATB2) is a master regulator of gene expression. Mutations of the SATB2 gene results in the SATB2-associated syndrome (SAS), a genetic disorder characterized by neurodevelopmental...
5.
Sampani K, Ness S, Tuz-Zahra F, Aytan N, Spurlock E, Alluri S, et al.
Alzheimers Res Ther . 2024 Aug; 16(1):192. PMID: 39187891
Background: Protein biomarkers have been broadly investigated in cerebrospinal fluid and blood for the detection of neurodegenerative diseases, yet a clinically useful diagnostic test to detect early, pre-symptomatic Alzheimer's disease...
6.
Ouyang X, Collu R, Benavides G, Tian R, Darley-Usmar V, Xia W, et al.
Curr Alzheimer Res . 2024 Jun; 21(3):183-200. PMID: 38910422
Background: The pathological manifestations of Alzheimer's disease (AD) include not only brain amyloid β protein (Aβ) containing neuritic plaques and hyperphosphorylated tau (p-- tau) containing neurofibrillary tangles but also microgliosis,...
7.
Hu D, Chen M, Li X, Morin P, Daley S, Han Y, et al.
bioRxiv . 2024 Jun; PMID: 38853824
One Sentence Summary: An apolipoprotein E (ApoE) ε4-dependent alteration of CD4 T cell subpopulation in peripheral blood is associated with neuroinflammation in patients with Alzheimer's disease.
8.
Aguilar B, Jasuja G, Li X, Shishova E, Palacios N, Berlowitz D, et al.
J Alzheimers Dis . 2024 May; 99(3):1065-1075. PMID: 38788073
Background: Diagnostic codes can be instrumental for case identification in Alzheimer's disease (AD) research; however, this method has known limitations and cannot distinguish between disease stages. Clinical notes may offer...
9.
Morin P, Aguilar B, Berlowitz D, Zhang R, Monfared A, Zhang Q, et al.
Alzheimer Dis Assoc Disord . 2024 May; 38(2):195-200. PMID: 38755757
Purpose: We aimed to examine the clinical characteristics of US veterans who underwent neurocognitive test score-based assessments of Alzheimer disease (AD) stage in the Veterans Affairs Healthcare System (VAHS). Methods:...
10.
OConnor M, Aguilar B, Nguyen A, Berlowitz D, Zhang R, Monfared A, et al.
Mil Med . 2024 Apr; 189(7-8):1409-1413. PMID: 38668648
Introduction: The benefits of early detection of Alzheimer's disease (AD) have become increasingly recognized. Veterans with mental health conditions (MHCs) may be less likely to receive a specific AD diagnosis...