Wassim Elyaman
Overview
Explore the profile of Wassim Elyaman including associated specialties, affiliations and a list of published articles.
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62
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3516
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Recent Articles
11.
Dressman D, Buttrick T, Cimpean M, Bennett D, Menon V, Bradshaw E, et al.
Hum Mol Genet
. 2022 May;
31(19):3355-3366.
PMID: 35640154
Recent studies identifying expression quantitative trait loci (eQTLs) in immune cells have uncovered important links between disease risk alleles and gene expression trends in monocytes, T cells and other cell...
12.
Dressman D, Elyaman W
Neuroscientist
. 2021 Jun;
28(4):335-348.
PMID: 34160330
T cells play a central role in homeostasis and host defense against infectious diseases. T cell dysregulation can lead to recognizing self-antigens as foreign antigens, causing a detrimental autoimmune response....
13.
Olah M, Menon V, Habib N, Taga M, Ma Y, Yung C, et al.
Nat Commun
. 2020 Dec;
11(1):6129.
PMID: 33257666
The extent of microglial heterogeneity in humans remains a central yet poorly explored question in light of the development of therapies targeting this cell type. Here, we investigate the population...
14.
Frangieh M, McHenry A, Phillips R, Ye C, Bernier A, Laffel L, et al.
Clin Immunol
. 2020 Jun;
217:108498.
PMID: 32531345
Interleukin (IL)-27 is a pleiotropic cytokine that initially was described as being pro-inflammatory and an inducer of T helper (Th)1 cells. In contrast, it has also been described as an...
15.
Ruan C, Sun L, Kroshilina A, Beckers L, De Jager P, Bradshaw E, et al.
Brain Behav Immun
. 2019 Oct;
83:180-191.
PMID: 31604143
Microglia are resident immune cells of the central nervous system (CNS). The exact role of microglia in CNS disorders is not clear due to lack of tools to discriminate between...
16.
Magee C, Murakami N, Borges T, Shimizu T, Safa K, Ohori S, et al.
Circulation
. 2019 Jul;
140(10):846-863.
PMID: 31266349
Background: Transplantation is the treatment of choice for many patients with end-stage organ disease. Despite advances in immunosuppression, long-term outcomes remain suboptimal, hampered by drug toxicity and immune-mediated injury, the...
17.
Olah M, Patrick E, Villani A, Xu J, White C, Ryan K, et al.
Nat Commun
. 2018 Feb;
9(1):539.
PMID: 29416036
With a rapidly aging global human population, finding a cure for late onset neurodegenerative diseases has become an urgent enterprise. However, these efforts are hindered by the lack of understanding...
18.
Kaskow B, Buttrick T, Klein H, White C, Bourgeois J, Ferland R, et al.
Neurol Neuroimmunol Neuroinflamm
. 2018 Jan;
5(1):e414.
PMID: 29379820
Objective: To study the influence of the Abelson helper integration site 1 () locus associated with MS susceptibility on CD4 T cell function. Methods: We characterized the chromatin state of...
19.
Buttrick T, Wang W, Yung C, Trieu K, Patel K, Khoury S, et al.
Sci Rep
. 2018 Jan;
8(1):818.
PMID: 29339772
T helper 9 (Th9) cells are effector CD4 T cells that are characterized by the production of interleukin-9 (IL-9) and have been associated with allergic responses. Here, we found that...
20.
Ryan K, White C, Patel K, Xu J, Olah M, Replogle J, et al.
Sci Transl Med
. 2017 Dec;
9(421).
PMID: 29263232
Microglia are emerging as a key cell type in neurodegenerative diseases, yet human microglia are challenging to study in vitro. We developed an in vitro cell model system composed of...