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Wang-Xia Wang

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Articles 52
Citations 2829
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Recent Articles
1.
Niedowicz D, Wang W, Prajapati P, Zhong Y, Fister S, Rogers C, et al.
Brain Pathol . 2024 Oct; :e13312. PMID: 39438022
Mutations in the human granulin (GRN) gene are associated with multiple diseases, including dementia disorders such as frontotemporal dementia (FTD) and limbic-predominant age-related TDP-43 encephalopathy (LATE). We studied a Grn...
2.
Bao W, Pang P, Zhou X, Hu F, Xiong W, Chen K, et al.
Cell Death Differ . 2024 Apr; 31(8):1099. PMID: 38575681
No abstract available.
3.
Geleta U, Prajapati P, Bachstetter A, Nelson P, Wang W
Int J Mol Sci . 2024 Mar; 25(5). PMID: 38473893
Neurological diseases and neurotrauma manifest significant sex differences in prevalence, progression, outcome, and therapeutic responses. Genetic predisposition, sex hormones, inflammation, and environmental exposures are among many physiological and pathological factors...
4.
Niedowicz D, Wang W, Price D, Xie K, Patel E, Nelson P
Neurobiol Aging . 2023 May; 128:74-84. PMID: 37229849
Mouse models of hyper- and hypothyroidism were used to examine the effects of thyroid hormone (TH) dyshomeostasis on the aging mammalian brain. 13-14 month-old mice were treated for 4months with...
5.
Welden J, Margvelani G, Maquera K, Gudlavalleti B, Miranda Sardon S, Campos A, et al.
Nucleic Acids Res . 2022 Dec; 50(22):12979-12996. PMID: 36533443
Aggregation of the microtubule-associated protein tau characterizes tauopathies, including Alzheimer's disease and frontotemporal lobar degeneration (FTLD-Tau). Gene expression regulation of tau is complex and incompletely understood. Here we report that...
6.
Gal J, Katsumata Y, Zhu H, Srinivasan S, Chen J, Johnson L, et al.
Am J Pathol . 2021 Dec; 192(3):564-578. PMID: 34954207
The amygdala is vulnerable to multiple or "mixed" mis-aggregated proteins associated with neurodegenerative conditions that can manifest clinically with amnestic dementia; the amygdala region is often affected even at earliest...
7.
Prajapati P, Wang W, Pesina S, Geleta U, Springer J
Cell Mol Neurobiol . 2021 Nov; 43(1):423-429. PMID: 34761332
Sex is a key biological variable in traumatic brain injury (TBI) and plays a significant role in neuroinflammatory responses. However, the molecular mechanisms contributing to this sexually dimorphic neuroinflammatory response...
8.
Wang W, Springer J, Hatton K
Int J Mol Sci . 2021 Sep; 22(17). PMID: 34502401
Aneurysmal subarachnoid hemorrhage (aSAH) is a high mortality hemorrhagic stroke that affects nearly 30,000 patients annually in the United States. Approximately 30% of aSAH patients die during initial hospitalization and...
9.
Niedowicz D, Wang W, Price D, Nelson P
J Thyroid Res . 2021 Jul; 2021:9960188. PMID: 34257897
Thyroid hormone (TH) perturbation is a common medical problem. Because of substantial public health impact, prior researchers have studied hyper- and hypothyroidism in animal models. Although most prior research focused...
10.
Wang W, Springer J, Xie K, Fardo D, Hatton K
Front Mol Biosci . 2021 May; 8:657258. PMID: 34055880
Approximately one-third of aneurysmal subarachnoid hemorrhage (aSAH) patients develop delayed cerebral vasospasm (DCV) 3-10 days after aneurysm rupture resulting in additional, permanent neurologic disability. Currently, no validated biomarker is available...