Bernard R Wilfred
Overview
Explore the profile of Bernard R Wilfred including associated specialties, affiliations and a list of published articles.
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15
Citations
1003
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Recent Articles
1.
Nelson P, Wang W, Wilfred B, Wei A, Dimayuga J, Huang Q, et al.
J Neurochem
. 2015 Jun;
134(6):1026-39.
PMID: 26115089
ABCC9 genetic polymorphisms are associated with increased risk for various human diseases including hippocampal sclerosis of aging. The main goals of this study were 1 > to detect the ABCC9...
2.
Nelson P, Wang W, Partch A, Monsell S, Valladares O, Ellingson S, et al.
J Neuropathol Exp Neurol
. 2014 Dec;
74(1):75-84.
PMID: 25470345
Hippocampal sclerosis of aging (HS-Aging) is a common high-morbidity neurodegenerative condition in elderly persons. To understand the risk factors for HS-Aging, we analyzed data from the Alzheimer's Disease Genetics Consortium...
3.
Nelson P, Estus S, Abner E, Parikh I, Malik M, Neltner J, et al.
Acta Neuropathol
. 2014 Apr;
127(6):825-43.
PMID: 24770881
Hippocampal sclerosis of aging (HS-Aging) is a high-morbidity brain disease in the elderly but risk factors are largely unknown. We report the first genome-wide association study (GWAS) with HS-Aging pathology...
4.
Malik M, Simpson J, Parikh I, Wilfred B, Fardo D, Nelson P, et al.
J Neurosci
. 2013 Aug;
33(33):13320-5.
PMID: 23946390
Genome-wide association studies are identifying novel Alzheimer's disease (AD) risk factors. Elucidating the mechanism underlying these polymorphisms is critical to the validation process and, by identifying rate-limiting steps in AD...
5.
Nelson P, Wang W, Mao G, Wilfred B, Xie K, Jennings M, et al.
Nucleic Acids Res
. 2011 Jul;
39(18):8163-72.
PMID: 21724616
MicroRNAs (miRNAs) target mRNAs in human cells via complex mechanisms that are still incompletely understood. Using anti-Argonaute (anti-AGO) antibody co-immunoprecipitation, followed by microarray analyses and downstream bioinformatics, 'RIP-Chip' experiments enable...
6.
Madathil S, Nelson P, Saatman K, Wilfred B
Bioessays
. 2010 Nov;
33(1):21-6.
PMID: 21053309
No abstract available.
7.
Finnerty J, Wang W, Hebert S, Wilfred B, Mao G, Nelson P
J Mol Biol
. 2010 Aug;
402(3):491-509.
PMID: 20678503
The miR-15/107 group of microRNA (miRNA) gene is increasingly appreciated to serve key functions in humans. These miRNAs regulate gene expression involved in cell division, metabolism, stress response, and angiogenesis...
8.
Wang W, Wilfred B, Madathil S, Tang G, Hu Y, Dimayuga J, et al.
Am J Pathol
. 2010 May;
177(1):334-45.
PMID: 20489155
Granulin (GRN, or progranulin) is a protein involved in wound repair, inflammation, and neoplasia. GRN has also been directly implicated in frontotemporal dementia and may contribute to Alzheimer's disease pathogenesis....
9.
Wang W, Wilfred B, Xie K, Jennings M, Hu Y, Stromberg A, et al.
RNA Biol
. 2010 Apr;
7(3):373-80.
PMID: 20421741
MicroRNAs (miRNAs) guide Argonaute (AGO)-containing microribonucleoprotein (miRNP) complexes to target mRNAs.It has been assumed that miRNAs behave similarly to each other with regard to mRNA target recognition. The usual assumptions,...
10.
Nelson P, Dimayuga J, Wilfred B
Front Hum Neurosci
. 2010 Mar;
4:7.
PMID: 20204141
MicroRNAs (miRNAs) play key roles in gene expression regulation in both healthy and disease brains. To better understand those roles, it is necessary to characterize the miRNAs that are expressed...