W J Thompson
Overview
Explore the profile of W J Thompson including associated specialties, affiliations and a list of published articles.
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Articles
184
Citations
2249
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Recent Articles
1.
Mundt K, Dell L, Boffetta P, Beckett E, Lynch H, Desai V, et al.
BMC Cancer
. 2021 Mar;
21(1):227.
PMID: 33676443
Introduction: Although myelodysplastic syndrome (MDS), acute myeloid leukemia (AML), myeloproliferative neoplasms (MPN) - including chronic myeloid leukemia (CML) - and myelodysplastic/myeloproliferative neoplasms (MDS/MPN) are largely clinically distinct myeloid malignancies, epidemiological...
2.
Ellerton E, Thompson W, Rimer M
Neuroscience
. 2008 Apr;
153(4):975-85.
PMID: 18440155
Terminal Schwann cells (tSCs) are non-myelinating glia that wrap the nerve terminal at the neuromuscular junction. They are required for the maintenance of the neuromuscular synapse and are likely to...
3.
Mullershausen F, Russwurm M, Thompson W, Liu L, Koesling D, Friebe A
J Cell Biol
. 2001 Oct;
155(2):271-8.
PMID: 11604422
Most of the effects of the signaling molecule nitric oxide (NO) are mediated by cGMP, which is synthesized by soluble guanylyl cyclase and degraded by phosphodiesterases. Here we show that...
4.
Liu L, Li H, Underwood T, Lloyd M, David M, Sperl G, et al.
J Pharmacol Exp Ther
. 2001 Oct;
299(2):583-92.
PMID: 11602670
These studies report on the activation and induction of cGMP-dependent protein kinase (PKG) by exisulind and analogs and test the hypothesis that PKG is involved in the induction of apoptosis...
5.
Thompson W
Neuron
. 2001 Aug;
31(3):341-2.
PMID: 11516390
Synapses are lost during developmental synapse elimination. Until now, it has been impossible to follow elimination in the entirety of any neuron's branches and synapses. Using transgenic mice in which...
6.
Piazza G, Thompson W, Pamukcu R, Alila H, WHITEHEAD C, Liu L, et al.
Cancer Res
. 2001 May;
61(10):3961-8.
PMID: 11358813
Exisulind (Aptosyn) is a novel antineoplastic drug being developed for the prevention and treatment of precancerous and malignant diseases. In colon tumor cells, the drug induces apoptosis by a mechanism...
7.
Soh J, Mao Y, Liu L, Thompson W, Pamukcu R, Weinstein I
J Biol Chem
. 2001 Mar;
276(19):16406-10.
PMID: 11278263
We recently obtained evidence that treatment of human colon cancer cells with exisulind (sulindac sulfone) and related compounds induces apoptosis by activation of protein kinase G (PKG) and c-Jun kinase...
8.
Soh J, Mao Y, Kim M, Pamukcu R, Li H, Piazza G, et al.
Clin Cancer Res
. 2000 Oct;
6(10):4136-41.
PMID: 11051267
Sulindac sulfone (Exisulind) induces apoptosis and exhibits cancer chemopreventive activity, but in contrast to sulindac, it does not inhibit cyclooxygenases 1 or 2. We found that sulindac sulfone and two...
9.
Zhou L, Thompson W, Potter D
J Ocul Pharmacol Ther
. 2000 Sep;
16(4):317-22.
PMID: 10977127
The phosphodiesterases (PDE) activity in human trabecular meshwork cells (HTM-3) was investigated in this study in order to better understand the signal transduction pathways in the conventional outflow tract of...
10.
Thompson W, Piazza G, Li H, Liu L, Fetter J, Zhu B, et al.
Cancer Res
. 2000 Jul;
60(13):3338-42.
PMID: 10910034
Sulindac sulfone (exisulind), although a nonsteroidal anti-inflammatory drug derivative, induces apoptosis in tumor cells by a mechanism that does not involve cyclooxygenase inhibition. SW480 colon tumor cells contain guanosine 3',5'-monophosphate...