P M Epstein
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Explore the profile of P M Epstein including associated specialties, affiliations and a list of published articles.
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41
Citations
343
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Recent Articles
1.
Andreeva S, Dikkes P, Epstein P, Rosenberg P
J Neurosci
. 2001 Nov;
21(22):9068-76.
PMID: 11698617
cGMP has been implicated in the regulation of many essential functions in the brain, such as synaptic plasticity, phototransduction, olfaction, and behavioral state. Cyclic nucleotide phosphodiesterase (PDE) hydrolysis of cGMP...
2.
Paskind M, Johnston C, Epstein P, Timm J, Wickramasinghe D, Belanger E, et al.
Mamm Genome
. 2000 Dec;
11(12):1063-9.
PMID: 11130973
CDC25A is a member of a group of highly related, dual-specificity phosphatases that promote cell cycle phase transitions by regulating the activity of cyclin-dependent kinases. Here we report the cloning...
3.
Epstein P
Methods
. 1998 Apr;
14(1):21-33.
PMID: 9500855
Cyclic nucleotide phosphodiesterases (PDEs) are represented by a superfamily of structurally and functionally related enzymes of which more than 30 different forms have so far been identified and grouped into...
4.
Jiang X, Paskind M, Weltzien R, Epstein P
Cell Biochem Biophys
. 1998 Mar;
28(2-3):135-60.
PMID: 9515164
We reported previously that the gene for PDE-1B1 is induced in isolated human peripheral blood lymphocytes (HPBL) following mitogenic stimulation (Jiang, X., Li, J., Paskind, M., and Epstein, P.M. [1996]...
5.
Jiang X, Li J, Paskind M, Epstein P
Proc Natl Acad Sci U S A
. 1996 Oct;
93(20):11236-41.
PMID: 8855339
Cytosolic extracts from a human lymphoblastoid B-cell line, RPMI-8392, established from a patient with acute lymphocytic leukemia, contain two major forms of cyclic nucleotide phosphodiesterase (PDE): Ca2+-calmodulin dependent PDE (PDE1)...
6.
Yang Q, Paskind M, Bolger G, Thompson W, Repaske D, Cutler L, et al.
Biochem Biophys Res Commun
. 1994 Dec;
205(3):1850-8.
PMID: 7811274
A cDNA clone for cyclic GMP Stimulated Phosphodiesterase (cGSPDE; PDE2) was isolated from a rat brain cDNA library. The cDNA has an open reading frame which encodes a protein of...
7.
Mednieks M, Epstein P, Hachisu R, Hand A, Esquire R
Arch Oral Biol
. 1994 Oct;
39(10):869-75.
PMID: 7741656
This study was conducted to compare cyclic AMP-reactive proteins (cARP), the secretory form of regulatory (R) subunits of cyclic AMP-dependent protein kinase (PKA), and cyclic nucleotide phosphodiesterase (PDE) activity in...
8.
Mednieks M, Zaki A, Epstein P, Hachisu R, Hand A, Bodner J, et al.
Ann N Y Acad Sci
. 1993 Sep;
694:299-301.
PMID: 8215072
No abstract available.
9.
Smilowitz H, Aramli L, Xu D, Epstein P
Life Sci
. 1991 Jan;
49(1):29-37.
PMID: 1646922
Using O-phosphotyrosine as a substrate, human platelets were shown to contain a highly active phosphotyrosine phosphatase (PTPase) activity. This activity was potently inhibited by vanadate, molybdate, and HgCl2. About 80%...
10.
Jansson I, Curti M, Epstein P, Peterson J, Schenkman J
Arch Biochem Biophys
. 1990 Dec;
283(2):285-92.
PMID: 2275544
In our previous report we showed cytochrome b5 to be a competitive inhibitor of cAMP-dependent protein kinase (PKA) for interaction with cytochrome P450 (P450). While P450 was phosphorylated, cytochrome b5...