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W Gombert

Explore the profile of W Gombert including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 5
Citations 132
Followers 0
Related Specialties
Allergy & Immunology
General Medicine
Cell Biology
Top 10 Co-Authors
M Bofill
G Janossy
A N Akbar
N J Borthwick
M Salmon
D Pilling
H Huser
M Sparmann
H Kroger
F Whitelaw
Published In
J Exp Med
Mol Cell Probes
Immunology
Am J Pathol
Affiliations
Soon will be listed here.
Recent Articles
1.
Fibroblasts prevent apoptosis of IL-2-deprived T cells without inducing proliferation: a selective effect on Bcl-XL expression
Gombert W, Borthwick N, Wallace D, HYDE H, Bofill M, Pilling D, et al.
Immunology . 1996 Nov; 89(3):397-404. PMID: 8958053
The apoptosis of human cytokine-deprived activated T cells can be prevented by a soluble mediator secreted by fibroblasts, epithelial and endothelial cells, and this rescue occurs with fibroblasts from different...
2.
Presence of CD3+CD8+Bcl-2(low) lymphocytes undergoing apoptosis and activated macrophages in lymph nodes of HIV-1+ patients
Bofill M, Gombert W, Borthwick N, Akbar A, McLaughlin J, Lee C, et al.
Am J Pathol . 1995 Jun; 146(6):1542-55. PMID: 7778692
Infection with human immunodeficiency virus 1 causes profound changes in the lymph nodes of infected patients. In particular, large numbers of CD8+CD45RO+ T cells infiltrate both the paracortex and the...
3.
The specific recognition by macrophages of CD8+,CD45RO+ T cells undergoing apoptosis: a mechanism for T cell clearance during resolution of viral infections
Akbar A, Savill J, Gombert W, Bofill M, Borthwick N, Whitelaw F, et al.
J Exp Med . 1994 Nov; 180(5):1943-7. PMID: 7964470
During viral infections, CD8+,CD45RO+ T populations expand. These primed cells express abundant levels of cytoplasmic granules that contain perforin and TIA-1. Recent work has suggested that the majority of this...
4.
The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory
Akbar A, Borthwick N, Salmon M, Gombert W, Bofill M, Shamsadeen N, et al.
J Exp Med . 1993 Aug; 178(2):427-38. PMID: 8340752
The bcl-2 gene product has been shown to prevent apoptotic cell death. We have now investigated the bcl-2 protein expression by resting and activated mature T cell populations. Freshly isolated...
5.
Proto-oncogene expression in cultured synovial fibroblasts of patients with rheumatoid arthritis
Anders M, Krohn K, Kroger H, Huser H, Sparmann M, Meissner A, et al.
Mol Cell Probes . 1991 Jun; 5(3):207-13. PMID: 1870583
Total RNA was isolated from cultured synovial fibroblasts of nine patients with rheumatoid arthritis and two controls (cruciate ligament ruptures). RNA was dot-blotted and hybridized with nine different, cloned cellular...