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W E Highsmith

Explore the profile of W E Highsmith including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 410
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Recent Articles
1.
McWilliams R, Highsmith W, Rabe K, de Andrade M, Tordsen L, Holtegaard L, et al.
Gut . 2005 Oct; 54(11):1661-2. PMID: 16227367
No abstract available.
2.
Barletta J, Edelman D, Highsmith W, Constantine N
J Virol Methods . 2005 Jun; 127(2):154-64. PMID: 15921765
Pathologic prion protein (PrP(Sc)), implicated in transmissible spongiform encephalopathies, is detected by antibody-based tests or bioassays to confirm the diagnosis of prion diseases. Presently, the Western blot or an ELISA...
3.
Monaghan K, Highsmith W, Amos J, Pratt V, Roa B, Friez M, et al.
Genet Med . 2004 Sep; 6(5):421-5. PMID: 15371907
Purpose: We expect that the mutation panel currently recommended for preconception/prenatal CF carrier screening will be modified as new information is learned regarding the phenotype associated with specific mutations and...
4.
Wang J, Coombes K, Highsmith W, Keating M, Abruzzo L
Bioinformatics . 2004 Jul; 20(17):3166-78. PMID: 15231529
Motivation: A major focus of current cancer research is to identify genes that can be used as markers for prognosis and diagnosis, and as targets for therapy. Microarray technology has...
5.
Hiatt K, Highsmith W
Hum Pathol . 2002 Aug; 33(6):680. PMID: 12152170
No abstract available.
6.
Ramdas L, Coombes K, Baggerly K, Abruzzo L, Highsmith W, Krogmann T, et al.
Genome Biol . 2001 Dec; 2(11):RESEARCH0047. PMID: 11737946
Background: A key assumption in the analysis of microarray data is that the quantified signal intensities are linearly related to the expression levels of the corresponding genes. To test this...
7.
Karp J, Lancet J, Kaufmann S, End D, Wright J, Bol K, et al.
Blood . 2001 May; 97(11):3361-9. PMID: 11369625
R115777 is a nonpeptidomimetic enzyme-specific inhibitor of farnesyl protein transferase (FT) that was developed as a potential inhibitor of Ras protein signaling, with antitumor activity in preclinical models. This study...
8.
King Jr J, Treanor J, Fast P, Wolff M, Yan L, Iacuzio D, et al.
J Infect Dis . 2000 Feb; 181(2):725-8. PMID: 10669363
Fifty-seven human immunodeficiency virus (HIV)-infected (CDC class A1-2) and 54 non-HIV-infected adults, not prescreened for influenza susceptibility, were randomized to receive trivalent live attenuated influenza vaccine (LAIV) or placebo intranasally....
9.
Abdel-Hamid M, Edelman D, Highsmith W, Constantine N
J Hum Virol . 1999 Apr; 1(1):58-65. PMID: 10195232
Objectives: To compare the performance of reverse transcription followed by the polymerase chain reaction (RT-PCR), without RNA purification, with the performance of classic protocols. Study Design/methods: Direct and classic techniques...
10.
Strovel J, Abruzzo L, Highsmith W, Stamberg J
Mod Pathol . 1998 Oct; 11(10):957-62. PMID: 9796722
Telomerase is a ribonucleoprotein that uses its internal RNA component as a template for synthesis of telomeric DNA on the ends of chromosomes after each round of cell division. It...