Vundavalli V V S Murty
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Explore the profile of Vundavalli V V S Murty including associated specialties, affiliations and a list of published articles.
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18
Citations
895
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Recent Articles
1.
Maurer M, Su T, Saal L, Koujak S, Hopkins B, Barkley C, et al.
Cancer Res
. 2009 Jul;
69(15):6299-306.
PMID: 19602588
Lesions of ERBB2, PTEN, and PIK3CA activate the phosphatidylinositol 3-kinase (PI3K) pathway during cancer development by increasing levels of phosphatidylinositol-3,4,5-triphosphate (PIP(3)). 3-Phosphoinositide-dependent kinase 1 (PDK1) is the first node of...
2.
Szabolcs M, Keniry M, Simpson L, Reid L, Koujak S, Schiff S, et al.
Am J Pathol
. 2008 Dec;
174(1):276-86.
PMID: 19095950
Mutations in the phosphatase and tensin homologue (PTEN)/phosphatidylinositol-3 kinase-alpha (PI3K) signaling pathway are frequently found in human cancer. In addition, Pten(+/-) mice develop tumors in multiple organs because of the...
3.
Saal L, Gruvberger-Saal S, Persson C, Lovgren K, Jumppanen M, Staaf J, et al.
Nat Genet
. 2007 Dec;
40(1):102-7.
PMID: 18066063
Basal-like breast cancer (BBC) is a subtype of breast cancer with poor prognosis. Inherited mutations of BRCA1, a cancer susceptibility gene involved in double-strand DNA break (DSB) repair, lead to...
4.
Laufer M, Nandula S, Modi A, Wang S, Jasin M, Murty V, et al.
J Biol Chem
. 2007 Sep;
282(47):34325-33.
PMID: 17848578
The BRCA1 tumor suppressor exists as a heterodimeric complex with BARD1, and this complex is thought to mediate many of the functions ascribed to BRCA1, including its role in tumor...
5.
Memeo L, Jhang J, Assaad A, McKiernan J, Murty V, Hibshoosh H, et al.
Am J Clin Pathol
. 2007 Jan;
127(2):225-9.
PMID: 17210525
Immunohistochemical staining for cytokeratin 7 (CK7), KIT, and PAX2 expression was performed on 91 renal neoplasms, 37 conventional (clear cell) renal cell carcinomas (CRCCs), 20 papillary RCCs (PRCCs), 11 chromophobe...
6.
Puc J, Keniry M, Li H, Pandita T, Choudhury A, Memeo L, et al.
Cancer Cell
. 2005 Feb;
7(2):193-204.
PMID: 15710331
Pten-/- cells display a partially defective checkpoint in response to ionizing radiation (IR). The checkpoint defect was traced to the ability of AKT to phosphorylate CHK1 at serine 280, since...
7.
Jakob J, Nagase S, Gazdar A, Chien M, Morozova I, Russo J, et al.
Genes Chromosomes Cancer
. 2005 Jan;
42(4):372-83.
PMID: 15645498
Loss of chromosome arm 18q is a common event in human pancreatic, colon, and breast cancers and is often interpreted as representing loss of one or more tumor-suppressor genes. In...
8.
Li C, Kim C, Margolin A, Guo M, Zhu J, Mason J, et al.
Am J Pathol
. 2004 Dec;
165(6):1943-53.
PMID: 15579438
Gain-of-function mutations in exon 3 of beta-catenin (CTNNB1) are specific for Wilms' tumors that have lost WT1, but 50% of WT1-mutant cases lack such "hot spot" mutations. To ask whether...
9.
Nandula S, Borczuk A, Murty V
Cancer Genet Cytogenet
. 2004 Jul;
152(2):169-71.
PMID: 15262441
No abstract available.
10.
Koul S, McKiernan J, Narayan G, Houldsworth J, Bacik J, Dobrzynski D, et al.
Mol Cancer
. 2004 May;
3:16.
PMID: 15149548
Background: Male germ cell tumor (GCT) is a highly curable malignancy, which exhibits exquisite sensitivity to cisplatin treatment. The genetic pathway(s) that determine the chemotherapy sensitivity in GCT remain largely...