Vishwanath R Lingappa
Overview
Explore the profile of Vishwanath R Lingappa including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
632
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Recent Articles
1.
Lingappa A, Akintunde O, Samueli E, Ewald C, Michon M, Ziari N, et al.
Open Biol
. 2024 Dec;
14(12):240210.
PMID: 39689856
Two structurally unrelated small molecule chemotypes, represented by compounds PAV-617 and PAV-951, with antiviral activity in cell culture against Mpox virus (formerly known as monkeypox virus) and human immunodeficiency virus...
2.
Michon M, Muller-Schiffmann A, Lingappa A, Yu S, Du L, Deiter F, et al.
Open Biol
. 2024 Jun;
14(6):230363.
PMID: 38889796
We present a novel small molecule antiviral chemotype that was identified by an unconventional cell-free protein synthesis and assembly-based phenotypic screen for modulation of viral capsid assembly. Activity of PAV-431,...
3.
Du L, Deiter F, Bouzidi M, Billaud J, Simmons G, Dabral P, et al.
Commun Biol
. 2024 Apr;
7(1):486.
PMID: 38649430
The ongoing evolution of SARS-CoV-2 to evade vaccines and therapeutics underlines the need for innovative therapies with high genetic barriers to resistance. Therefore, there is pronounced interest in identifying new...
4.
Michon M, Muller-Schiffmann A, Lingappa A, Yu S, Du L, Deiter F, et al.
bioRxiv
. 2021 Dec;
PMID: 34931190
We present a novel small molecule antiviral chemotype that was identified by an unconventional cell-free protein synthesis and assembly-based phenotypic screen for modulation of viral capsid assembly. Activity of PAV-431,...
5.
Alpert E, Akhavan A, Gruzman A, Hansen W, Lehrer-Graiwer J, Hall S, et al.
Biosci Rep
. 2021 Oct;
41(10).
PMID: 34677582
The role of human prostatic acid phosphatase (PAcP, P15309|PPAP_HUMAN) in prostate cancer was investigated using a new proteomics tool termed signal sequence swapping (replacement of domains from the native cleaved...
6.
Alpert E, Akhavan A, Gruzman A, Hansen W, Lehrer-Graiwer J, Hall S, et al.
Biosci Rep
. 2021 Oct;
PMID: 34605872
The role of human prostatic acid phosphatase (PAcP, P15309|PPAP_HUMAN) in prostate cancer was investigated using a new proteomic tool termed signal sequence swapping (replacement of domains from the native cleaved...
7.
Galli L, Anderson M, Gabriel Fraley J, Sanchez L, Bueno R, Hernandez D, et al.
Open Biol
. 2021 Jun;
11(6):200400.
PMID: 34186010
Wnt gradients elicit distinct cellular responses, such as proliferation, specification, differentiation and survival in a dose-dependent manner. Porcupine (PORCN), a membrane-bound O-acyl transferase (MBOAT) that resides in the endoplasmic reticulum,...
8.
Priyamvada L, Burgado J, Baker-Wagner M, Kitaygorodskyy A, Olson V, Lingappa V, et al.
Antiviral Res
. 2021 May;
191:105086.
PMID: 33992710
Decades after the eradication of smallpox and the discontinuation of routine smallpox vaccination, over half of the world's population is immunologically naïve to variola virus and other orthopoxviruses (OPXVs). Even...
9.
Lingappa J, Lingappa V, Reed J
Viruses
. 2021 Apr;
13(3).
PMID: 33802145
The concerning increase in HIV-1 resistance argues for prioritizing the development of host-targeting antiviral drugs because such drugs can offer high genetic barriers to the selection of drug-resistant viral variants....
10.
Muller-Schiffmann A, Trossbach S, Lingappa V, Korth C
Trends Neurosci
. 2020 Dec;
44(5):352-365.
PMID: 33317827
The ability of viruses to evolve several orders of magnitude faster than their host cells has enabled them to exploit host cellular machinery by selectively recruiting multiprotein complexes (MPCs) for...