Andreas Muller-Schiffmann
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Explore the profile of Andreas Muller-Schiffmann including associated specialties, affiliations and a list of published articles.
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34
Citations
764
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Recent Articles
1.
Lingappa A, Akintunde O, Samueli E, Ewald C, Michon M, Ziari N, et al.
Open Biol
. 2024 Dec;
14(12):240210.
PMID: 39689856
Two structurally unrelated small molecule chemotypes, represented by compounds PAV-617 and PAV-951, with antiviral activity in cell culture against Mpox virus (formerly known as monkeypox virus) and human immunodeficiency virus...
2.
Michon M, Muller-Schiffmann A, Lingappa A, Yu S, Du L, Deiter F, et al.
Open Biol
. 2024 Jun;
14(6):230363.
PMID: 38889796
We present a novel small molecule antiviral chemotype that was identified by an unconventional cell-free protein synthesis and assembly-based phenotypic screen for modulation of viral capsid assembly. Activity of PAV-431,...
3.
van Gerresheim E, Muller-Schiffmann A, Schable S, Koopmans B, Loos M, Korth C
Neuropathol Appl Neurobiol
. 2023 Mar;
49(2):e12895.
PMID: 36861420
No abstract available.
4.
Michon M, Muller-Schiffmann A, Lingappa A, Yu S, Du L, Deiter F, et al.
bioRxiv
. 2021 Dec;
PMID: 34931190
We present a novel small molecule antiviral chemotype that was identified by an unconventional cell-free protein synthesis and assembly-based phenotypic screen for modulation of viral capsid assembly. Activity of PAV-431,...
5.
Bocharov E, Gremer L, Urban A, Okhrimenko I, Volynsky P, Nadezhdin K, et al.
J Med Chem
. 2021 Nov;
64(22):16464-16479.
PMID: 34739758
Alzheimer's disease (AD) is a severe neurodegenerative pathology with no effective treatment known. Toxic amyloid-β peptide (Aβ) oligomers play a crucial role in AD pathogenesis. AlldEnantiomeric peptide D3 and its...
6.
van Gerresheim E, Herring A, Gremer L, Muller-Schiffmann A, Keyvani K, Korth C
Neuropathol Appl Neurobiol
. 2020 Dec;
47(5):603-610.
PMID: 33338256
Objectives: The heterogeneity of Amyloid-beta (Aβ) plaque load in patients with Alzheimer's disease (AD) has puzzled neuropathology. Since brain Aβ plaque load does not correlate with cognitive decline, neurotoxic soluble...
7.
Muller-Schiffmann A, Trossbach S, Lingappa V, Korth C
Trends Neurosci
. 2020 Dec;
44(5):352-365.
PMID: 33317827
The ability of viruses to evolve several orders of magnitude faster than their host cells has enabled them to exploit host cellular machinery by selectively recruiting multiprotein complexes (MPCs) for...
8.
Ramani A, Muller L, Ostermann P, Gabriel E, Abida-Islam P, Muller-Schiffmann A, et al.
EMBO J
. 2020 Sep;
39(20):e106230.
PMID: 32876341
COVID-19 pandemic caused by SARS-CoV-2 infection is a public health emergency. COVID-19 typically exhibits respiratory illness. Unexpectedly, emerging clinical reports indicate that neurological symptoms continue to rise, suggesting detrimental effects...
9.
Martins S, Muller-Schiffmann A, Erichsen L, Bohndorf M, Wruck W, Sleegers K, et al.
Int J Mol Sci
. 2020 Jul;
21(12).
PMID: 32630447
Genes associated with immune response and inflammation have been identified as genetic risk factors for late-onset Alzheimer´s disease (LOAD). The rare R47H variant within triggering receptor expressed on myeloid cells...
10.
Marreiros R, Muller-Schiffmann A, Trossbach S, Prikulis I, Hansch S, Weidtkamp-Peters S, et al.
Proc Natl Acad Sci U S A
. 2020 Mar;
117(12):6741-6751.
PMID: 32152117
Neurodegenerative diseases feature specific misfolded or misassembled proteins associated with neurotoxicity. The precise mechanisms by which protein aggregates first arise in the majority of sporadic cases have remained unclear. Likely,...