Vikas Prabhakar
Overview
Explore the profile of Vikas Prabhakar including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
15
Citations
424
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Williams M, Oliphant M, Au V, Liu C, Baril C, OFlanagan C, et al.
Nat Genet
. 2024 Nov;
56(12):2753-2762.
PMID: 39567747
The prevalence and nature of somatic copy number alterations (CNAs) in breast epithelium and their role in tumor initiation and evolution remain poorly understood. Using single-cell DNA sequencing (49,238 cells)...
2.
Williams M, Oliphant M, Au V, Liu C, Baril C, OFlanagan C, et al.
bioRxiv
. 2024 May;
PMID: 38746396
Cancer-associated mutations have been documented in normal tissues, but the prevalence and nature of somatic copy number alterations and their role in tumor initiation and evolution is not well understood....
3.
Dahl S, Koh J, Prabhakar V, Niklason L
Cell Transplant
. 2017 Sep;
12(6):659-666.
PMID: 28866947
More than 570,000 coronary artery bypass grafts are implanted each year, creating an important demand for small-diameter vascular grafts. For patients who lack adequate internal mammary artery or saphenous vein,...
4.
Prabhakar V, Capila I, Sasisekharan R
Methods Mol Biol
. 2009 Mar;
534:147-56.
PMID: 19277554
There is accumulating evidence of the importance of linear polysaccharides in modulating biological phenomena in both the normal and the diseased states. This layer of regulation results from interactions between...
5.
Prabhakar V, Capila I, Sasisekharan R
Methods Mol Biol
. 2009 Mar;
534:331-40.
PMID: 19277541
Interactions between glycans and proteins are central to many of the regulatory processes within biology. The development of analytical methodologies that enable structural characterization of glycosaminoglycan oligosaccharides has fostered improved...
6.
Prabhakar V, Capila I, Soundararajan V, Raman R, Sasisekharan R
J Biol Chem
. 2008 Oct;
284(2):974-82.
PMID: 18849565
Chondroitin lyases (or chondroitinases) are a family of enzymes that depolymerize chondroitin sulfate (CS) and dermatan sulfate (DS) galactosaminoglycans, which have gained prominence as important players in central nervous system...
7.
Prabhakar V, Sasisekharan R
Adv Pharmacol
. 2007 Jan;
53:69-115.
PMID: 17239763
No abstract available.
8.
Prabhakar V, Capila I, Raman R, Srinivasan A, Bosques C, Pojasek K, et al.
Biochemistry
. 2006 Sep;
45(37):11130-9.
PMID: 16964974
The chondroitinases are bacterial lyases that specifically cleave chondroitin sulfate and/or dermatan sulfate glycosaminoglycans. One of these enzymes, chondroitinase ABC I from Proteus vulgaris, has the broadest substrate specificity and...
9.
Sasisekharan R, Raman R, Prabhakar V
Annu Rev Biomed Eng
. 2006 Jul;
8:181-231.
PMID: 16834555
Extracellular modulation of phenotype is an emerging paradigm in this current postgenomics age of molecular and cell biology. Glycosaminoglycans (GAGs) are primary components of the cell surface and the cell-extracellular...
10.
Prabhakar V, Raman R, Capila I, Bosques C, Pojasek K, Sasisekharan R
Biochem J
. 2005 Aug;
390(Pt 2):395-405.
PMID: 16108757
cABC I (chondroitinase ABC I) from Proteus vulgaris is a GalAG (galactosaminoglycan) depolymerizing lyase that cleaves its substrates at the glycosidic bond via beta-elimination. cABC I cleaves a particularly broad...