Vikas N Telvekar
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Explore the profile of Vikas N Telvekar including associated specialties, affiliations and a list of published articles.
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11
Citations
61
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Recent Articles
1.
Gokhale K, Telvekar V
Chem Biol Drug Des
. 2020 Aug;
97(1):148-156.
PMID: 32745362
Emergence of MDR-TB and XDR-TB led to the failure of available anti-tubercular drugs. In order to explore, identify and develop new anti-tubercular drugs, novel peptidomimetic series of Mtb-peptide deformylase (PDF)...
2.
Mali J, Sutar Y, Pahelkar A, Verma P, Telvekar V
Chem Biol Drug Des
. 2019 Oct;
95(1):174-181.
PMID: 31581353
The discovery of antibiotics around the middle twentieth century led to a decrease in the interest in antimycobacterial fatty acids. In order to re-establish the importance of naturally abundant fatty...
3.
Sutar Y, Mali J, Telvekar V, Rajmani R, Singh A
Eur J Med Chem
. 2019 Sep;
183:111713.
PMID: 31557610
Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) has become the world's leading killer disease due to a single infectious agent which survives in the host macrophage for the indefinite period....
4.
Sutar Y, Telvekar V
Mater Sci Eng C Mater Biol Appl
. 2018 Sep;
92:393-406.
PMID: 30184765
The effective delivery of low potency anticancer drug is a major challenge. The present study introduces the novel chitosan-polylactic acid (CS-PLA)-drug conjugate and its transferrin receptor targeted polyelectrolyte complex nanoparticles...
5.
Siddiki A, Bairwa V, Telvekar V
Comb Chem High Throughput Screen
. 2014 Mar;
17(7):630-8.
PMID: 24625232
A series of structurally novel, (E)-N'-(4-aryloxybenzylidene)-1H-benzimidazole-2-carbohydrazide derivatives were synthesized by molecular hybridization technique. All these compounds were evaluated against Mycobacterium tuberculosis H37Rv strains using Resazurin Microtiter assay (REMA) method. These...
6.
Patel K, Telvekar V
Eur J Med Chem
. 2014 Feb;
75:43-56.
PMID: 24530490
The analogs of N-[4-(piperazin-1-yl)phenyl]cinnamamide were designed and synthesized by molecular hybridization approach in which part C of the designed molecule was linked through amide and carbamate functionality that improves the...
7.
Bairwa V, Telvekar V
Comb Chem High Throughput Screen
. 2012 Nov;
16(3):244-7.
PMID: 23176058
Molecular hybridization approach was used to synthesize substituted 2-(2-(4-aryl oxy benzylidene) hydrazinyl)benzo thiazole derivatives with 2-hydrazinobenzothiazole and 4-(alicycli/aryl/biaryl/heteroaryl oxy)benzaldehyde as new anti-TB agents. The synthesized compounds, when tested against H37Rv...
8.
Novel N'-benzylidene benzofuran-3-carbohydrazide derivatives as antitubercular and antifungal agents
Telvekar V, Belubbi A, Bairwa V, Satardekar K
Bioorg Med Chem Lett
. 2012 Feb;
22(6):2343-6.
PMID: 22365752
Tuberculosis constitutes today a serious threat to human health worldwide, aggravated by the increasing number of identified multi-drug resistant strains of Mycobacterium tuberculosis (Mtb), its causative agent, as well as...
9.
Telvekar V, Bairwa V, Satardekar K, Bellubi A
Bioorg Med Chem Lett
. 2011 Nov;
22(1):649-52.
PMID: 22079026
A series of structurally novel, substituted 2-(2-(4-aryloxybenzylidene) hydrazinyl)benzothiazole derivatives incorporating 2-hydrazinyl benzothiazole and 4-(aryloxy)benzaldehyde were designed and synthesized using molecular hybridization approach. All the synthesized compounds exhibited promising activity (MIC...
10.
Telvekar V, Patel K
Chem Biol Drug Des
. 2011 Apr;
78(1):150-60.
PMID: 21518263
To elucidate the crucial structural features for the HIV-1 integrase inhibitors, a three-dimensional pharmacophore model was developed based on N-methyl pyrimidones, dihydroxypyrimidines, and bicyclic pyrimidinones derivatives using Phase. N-methyl pyrimidone...