Vijaya Ramachandran
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Explore the profile of Vijaya Ramachandran including associated specialties, affiliations and a list of published articles.
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Recent Articles
21.
Deniger D, Maiti S, Mi T, Switzer K, Ramachandran V, Hurton L, et al.
Clin Cancer Res
. 2014 May;
20(22):5708-19.
PMID: 24833662
Purpose: To activate and propagate populations of γδ T cells expressing polyclonal repertoire of γ and δ T-cell receptor (TCR) chains for adoptive immunotherapy of cancer, which has yet to...
22.
Arumugam T, Ramachandran V, Sun D, Peng Z, Pal A, Maxwell D, et al.
Mol Cancer Ther
. 2013 Jan;
12(5):654-62.
PMID: 23303403
We have previously shown that the antiallergic drug cromolyn blocks S100P interaction with its receptor receptor for advanced glycation end product (RAGE) and improves gemcitabine effectiveness in pancreatic ductal adenocarcinoma...
23.
Charo C, Holla V, Arumugam T, Hwang R, Yang P, DuBois R, et al.
Pancreas
. 2012 Oct;
42(3):467-74.
PMID: 23090667
Objectives: Pancreatic stellate cells are source of dense fibrotic stroma, a constant pathological feature of chronic pancreatitis and pancreatic adenocarcinoma. We observed correlation between levels of cyclooxygenase 2 (COX-2) and...
24.
Aggarwal G, Ramachandran V, Javeed N, Arumugam T, Dutta S, Klee G, et al.
Gastroenterology
. 2012 Sep;
143(6):1510-1517.e1.
PMID: 22960655
Background & Aims: New-onset diabetes in patients with pancreatic cancer is likely to be a paraneoplastic phenomenon caused by tumor-secreted products. We aimed to identify the diabetogenic secretory product(s) of...
25.
Song S, Ji B, Ramachandran V, Wang H, Hafley M, Logsdon C, et al.
PLoS One
. 2012 Aug;
7(8):e42699.
PMID: 22900040
Pancreatic cancer (PDAC) is a lethal disease with a five-year survival of 3-5%. Mutations in K-Ras are found in nearly all cases, but K-Ras mutations alone are not sufficient for...
26.
Hwang R, Moore T, Hattersley M, Scarpitti M, Yang B, Devereaux E, et al.
Mol Cancer Res
. 2012 Aug;
10(9):1147-57.
PMID: 22859707
Purpose: The Hedgehog (Hh) pathway has emerged as an important pathway in multiple tumor types and is thought to be dependent on a paracrine signaling mechanism. The purpose of this...
27.
Arumugam T, Ramachandran V, Gomez S, Schmidt A, Logsdon C
Clin Cancer Res
. 2012 Jun;
18(16):4356-64.
PMID: 22718861
Purpose: The receptor for advanced glycation end products (RAGE) contributes to multiple pathologies, including diabetes, arthritis, neurodegenerative diseases, and cancer. Despite the obvious need, no RAGE inhibitors are in common...
28.
Arumugam T, Brandt W, Ramachandran V, Moore T, Wang H, May F, et al.
Pancreas
. 2011 Jul;
40(6):815-22.
PMID: 21747314
Objectives: Trefoil factor 1 (TFF1) is a stable secretory protein expressed widely in the gastrointestinal mucosa that is also expressed in pancreatic ductal adenocarcinoma (PDAC). In the current study, we...
29.
Chowdhury R, Le H, Ramachandran V
IEEE/ACM Trans Comput Biol Bioinform
. 2010 Jul;
7(3):495-510.
PMID: 20671320
We present efficient cache-oblivious algorithms for some well-studied string problems in bioinformatics including the longest common subsequence, global pairwise sequence alignment and three-way sequence alignment (or median), both with affine...
30.
Ramachandran V, Arumugam T, Langley R, Hwang R, Vivas-Mejia P, Sood A, et al.
PLoS One
. 2009 Oct;
4(10):e7502.
PMID: 19847298
Background: Adrenomedullin (AM) is highly expressed in pancreatic cancer and stimulates pancreatic cancer cells leading to increased tumor growth and metastasis. The current study examines the role of specific AM...