Vijaya Ramachandran
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Explore the profile of Vijaya Ramachandran including associated specialties, affiliations and a list of published articles.
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Recent Articles
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Pandita S, Ramachandran V, Balakrishnan P, Rolfs A, Brandau O, Eichler S, et al.
J Hum Genet
. 2019 Mar;
64(5):409-419.
PMID: 30816285
Autosomal Dominant Polycystic Kidney Disease (ADPKD) accounts for 2.6% of the patients with chronic kidney disease in India. ADPKD is caused by pathogenic variants in either PKD1 or PKD2 gene....
13.
Zhou L, Husted H, Moore T, Lu M, Deng D, Liu Y, et al.
Sci Transl Med
. 2018 Oct;
10(464).
PMID: 30355799
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, and it is unclear whether its stromal infiltrate contributes to its aggressiveness. Here, we demonstrate that Dickkopf-3 (DKK3) is produced by pancreatic...
14.
Pandita S, Maurya D, Ramachandran V, Verma J, Kohli S, Saxena R, et al.
Int J Mol Cell Med
. 2018 Apr;
6(3):164-173.
PMID: 29682488
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by a significant phenotypic variability in progression of the disease. Vascular endothelial growth factor () has been reported to play a major...
15.
Pavlidou E, Ramachandran V, Govender V, Wilson C, Das R, Vlachou V, et al.
Brain Dev
. 2016 Oct;
39(3):271-274.
PMID: 27793435
Pelizaeus-Merzbacher disease (PMD) is a rare, X-linked disorder characterized by hypomyelination of the Central Nervous System due to mutations in the PLP1 gene. Certain mutations of the PLP1 gene correlate...
16.
Cao J, Yang J, Ramachandran V, Arumugam T, Deng D, Li Z, et al.
Cell Physiol Biochem
. 2016 Jul;
39(2):740-50.
PMID: 27459514
Background/aims: The cell surface protein transmembrane 4 L6 family member 1 (TM4SF1) has been detected in various tumors and plays a major role in the development of cancer. We aimed...
17.
Cao J, Yang J, Ramachandran V, Arumugam T, Deng D, Li Z, et al.
PLoS One
. 2015 Dec;
10(12):e0144969.
PMID: 26709920
Background: TM4SF1 is overexpressed in pancreatic ductal adenocarcinoma (PDAC) and affects the development of this cancer. Also, multidrug resistance (MDR) is generally associated with tumor chemoresistance in pancreatic cancer. However,...
18.
Logsdon C, Arumugam T, Ramachandran V
Am J Physiol Gastrointest Liver Physiol
. 2015 Jul;
309(5):G283-91.
PMID: 26159697
Pancreatic ductal adenocarcinoma (PDAC) is relatively rare but extremely lethal. Standard cytotoxic therapeutics provide little benefit. To date, newer targeted therapeutics have also not been highly successful. Often novel therapeutics...
19.
Arumugam T, Deng D, Bover L, Wang H, Logsdon C, Ramachandran V
Mol Cancer Ther
. 2015 Feb;
14(4):941-51.
PMID: 25646014
Anterior gradient 2 (AGR2) promotes cancer growth, metastasis, and resistance to therapy via unknown mechanisms. We investigated the effects of extracellular AGR2 signaling through the orphan glycosylphosphatidylinositol-linked receptor C4.4A in...
20.
Roland C, Arumugam T, Deng D, Liu S, Philip B, Gomez S, et al.
Cancer Res
. 2014 Jun;
74(18):5301-10.
PMID: 24928781
The mechanisms that allow cancer cells to adapt to the typical tumor microenvironment of low oxygen and glucose and high lactate are not well understood. GPR81 is a lactate receptor...