Vijai Kumar Reddy Tangadanchu
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Explore the profile of Vijai Kumar Reddy Tangadanchu including associated specialties, affiliations and a list of published articles.
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19
Citations
157
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Recent Articles
1.
Qiu L, Jiang H, Zhou C, Tangadanchu V, Wang J, Huang T, et al.
Org Biomol Chem
. 2024 Jun;
22(26):5428-5453.
PMID: 38884683
Here we report our design and synthesis of 28 new fluorine-containing compounds as potential F-18 radiotracers for CNS imaging of sphingosine-1-phosphate receptor 1 (S1PR1), and determination of their binding potency...
2.
Zhao W, Xu J, Tangadanchu V, Zhou C
Eur J Med Chem
. 2023 May;
256:115452.
PMID: 37167780
The emergence of pathogenic and drug-resistant microorganisms seriously threatens public safety. This work constructed a unique type of thiazolyl hydrazineylidenyl indolones (THIs) to combat global microbial multidrug-resistance. Bioactive evaluation discovered...
3.
Zhang P, Tangadanchu V, Zhou C
Molecules
. 2022 Dec;
27(23).
PMID: 36500547
The invasion of pathogenic fungi poses nonnegligible threats to the human health and agricultural industry. This work exploited a family of hydroxyethyl naphthalimides as novel antifungal species with synergistic potential...
4.
Li F, Zhao W, Tangadanchu V, Meng J, Zhou C
Eur J Med Chem
. 2022 Jun;
239:114521.
PMID: 35716514
With the soaring of bacterial infection and drug resistance, it is imperative to exploit new efficient antibacterial agents. This work constructed a series of unique phenylhydrazone-based oxindole-thiolazoles to combat monstrous...
5.
Li F, Zhang P, Tangadanchu V, Li S, Zhou C
Bioorg Chem
. 2022 Mar;
122:105718.
PMID: 35255343
The dreadful bacterial resistance to clinical drugs calls for the development of novel antibacterials. This work developed a class of unique metronidazole-derived three-component hybrids as promising antibacterial therapeutic alternatives. Bioactive...
6.
Tangadanchu V, Sui Y, Zhou C
Bioorg Med Chem Lett
. 2021 Apr;
41:128030.
PMID: 33839249
Novel antibiotics are forced to be developed on account of multidrug-resistant bacteria with serious threats to human health. This work developed isatin-derived azoles as new potential antimicrobial agents. Bioactive assay...
7.
Tangadanchu V, Jiang H, Yu Y, Graham T, Liu H, Rogers B, et al.
Eur J Med Chem
. 2020 Sep;
206:112713.
PMID: 32919113
Sphingosine kinase (SphK) is primarily responsible for the production of Sphingosine-1-phosphate (S1P) that plays an important role in many biological and pathobiological processes including cancer, inflammation, neurological and cardiovascular disorders....
8.
Li Z, Tangadanchu V, Battini N, Bheemanaboina R, Zang Z, Zhang S, et al.
Eur J Med Chem
. 2019 Jul;
179:723-735.
PMID: 31284082
The biological resistance of methicillin-resistant staphylococcus aureus (MRSA) has pushed synthetic antibiotics to the forefront. To combat the resistance of MRSA, our new effort directed towards the development of novel...
9.
Li D, Bheemanaboina R, Battini N, Tangadanchu V, Fang X, Zhou C
Medchemcomm
. 2018 Oct;
9(9):1529-1537.
PMID: 30288226
A series of novel unique structural organophosphorus aminopyrimidines were developed as potential DNA-targeting membrane active inhibitors through an efficient one-pot procedure from aldehydes, phosphonate and aminopyrimidine. The biological assay revealed...
10.
Zhang Y, Damu G, Cui S, Mi J, Tangadanchu V, Zhou C
Medchemcomm
. 2018 Aug;
8(8):1631-1639.
PMID: 30108874
A series of triazoles as miconazole analogues was designed, synthesized and characterized by IR, NMR, MS and HRMS. All the newly prepared compounds were screened for their antifungal activities against...